Identification of Metal Oxide Nanoparticles in Histological Samples by Enhanced Darkfield Microscopy and Hyperspectral MappingGary A. Roth 1, Maria del Pilar Sosa Peña 1, Nicole M. Neu-Baker 1, Sahil Tahiliani 1, Sara A. Brenner 1
1Nanobioscience Constellation, SUNY Polytechnic Institute, Colleges of Nanoscale Science and Engineering
Enhanced darkfield microscopy and hyperspectral imaging with spectral mapping enable screening, localization, and identification of nanoscale materials in histological samples with improved speed and accuracy over traditional methods. The goal of this paper is to provide methods for darkfield imaging and hyperspectral mapping of metal oxide nanoparticles in histological samples.
