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6.6 : Carbocations

Carbocations are one of the reaction intermediates formed during several nucleophilic substitutions or elimination reactions. A carbocation is an electron-deficient species with the central carbon atom having six electrons and three bonded atoms. The central carbon in a carbocation is sp2 hybridized with trigonal planar geometry. It has an empty p orbital perpendicular to the plane of the structure that can accept electrons. Thus, carbocations act as strong electrophiles and may react with any nucleophile.

A methyl cation is the simplest form of carbocation, which has three hydrogen atoms attached to the central carbon. Each hydrogen atom can be replaced with an alkyl substituent to generate a primary, secondary or tertiary carbocation.

The stability of the carbocation can be estimated by the inductive effect and hyperconjugation phenomenon that directly depends on the number of alkyl substituents adjacent to the central positive carbon atom. Thus, the carbocation’s stability increases with the increase in the number of alkyl groups.

Tags
CarbocationsReaction IntermediatesNucleophilic SubstitutionsElimination ReactionsElectron deficient SpeciesSp2 HybridizedTrigonal Planar GeometryEmpty P OrbitalElectrophilesNucleophileMethyl CationAlkyl SubstituentPrimary CarbocationSecondary CarbocationTertiary CarbocationStabilityInductive EffectHyperconjugation Phenomenon

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6.6 : Carbocations

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.1 : Alkyl Halides

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.2 : Nucleophilic Substitution Reactions

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.3 : Nucleophiles

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6.4 : Electrophiles

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.5 : Leaving Groups

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.7 : SN2 Reaction: Kinetics

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.8 : SN2 Reaction: Mechanism

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6.9 : SN2 Reaction: Transition State

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.10 : SN2 Reaction: Stereochemistry

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.11 : SN1 Reaction: Kinetics

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.12 : SN1 Reaction: Mechanism

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.13 : SN1 Reaction: Stereochemistry

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.14 : Predicting Products: SN1 vs. SN2

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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6.15 : Elimination Reactions

Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

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