Name: Using 23Na Magnetic Resonance Imaging to Measure Sodium in Muscle Tissues
Uploaded: 2024-02-29T13:13:38
Description: All procedures involving human participants have been performed in compliance with the institutional, national, and international guidelines for human ...

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All procedures involving human participants have been performed in compliance with the institutional, national, and international guidelines for human welfare and have been reviewed by the local institutional review board.
1. Preparation of the phantom holder
<ol>
	<li>Four standard sodium solutions, including aqueous NaCl in the physiologic range of peripheral tissue sodium content 10-40 mmol/L, are embedded in a platform in the coil.</li>
</ol>
<stron...

using 23na magnetic resonance imaging to measure sodium in muscle tissues

This video demonstrates the quantification of sodium content in human tissues using sodium magnetic resonance imaging (23Na-MRI). The patient&#39;s lower leg is placed within the radiofrequency (RF) coil of the machine, and a three-dimensional gradient-echo sequence is performed. Multinuclear MRI images are generated using hydrogen and sodium nuclei to quantify sodium levels in various tissues.

Using 23Na Magnetic Resonance Imaging to Measure Sodium in Muscle Tissues

All procedures involving human participants have been performed in compliance with the institutional, national, and international guidelines for human ...

Place the patient&#39;s lower leg within the radiofrequency coil of the magnetic resonance imaging or MRI machine.
The coil contains various sodium concentrations as standards to measure tissue sodium accumulation.
Initiate a sodium-MRI scan.
The coil detects fluctuations in the MR signal intensity emitted from the tissue, influenced by the distribution and concentration of sodium ions. 
Obtain a total tissue sodium map displaying areas with varying color intensities corresponding to the sodium levels. 
Compare these intensities with standard sodium concentrations, which aid in measuring total tissue sodium levels. 
 Bright colors indicate higher levels, while darker colors indicate lower levels. 
 Next, capture signals corresponding to the fat and water content of the tissue to generate images of the non-muscle regions.
 Subtract non-muscle regions from the total tissue sodium map to generate a refined image and measure muscle tissue sodium content.

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Using ²³Na Magnetic Resonance Imaging to Measure Sodium in Muscle Tissues

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