Name: combining computer game-based behavioural experiments with high-density eeg and infrared gaze tracking
Uploaded: 2010-12-16T17:00:00
Description: Watch this Scientific Journal Video about Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking at JoVE.com

Este projecto é financiado pela Autism Speaks Pilot Research Grant # 2597 e pela Fundação Nacional de Ciência dos EUA Faculdade Early Career Development Award # BCS-0846892.

1. Projetar um jogo de vídeo divertido e informativo Cientificamente <ol><li> Aplicar um processo iterativo game design em que as preocupações de valor científico e jogabilidade informar-se mutuamente. Como um experimentador, você tem idéias como aos estímulos e paradigmas comportamentais que você quer ver construído em um jogo de computador. Porque você não é um designer de jogos, a tarefa de construir esses paradigmas em jogos pode parecer um detalhe que pode ser abordado depois que a ma...

<ol>
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S., Bavelier, D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effect+of+action+video+games+on+the+spatial+distribution+of+visuospatial+attention.">Effect of action video games on the spatial distribution of visuospatial attention.</a> Journal of Experimental Psychology Human Perception and Performance. 32, 1465-1478 (2006).</li><li>Green, C. S., Bavelier, D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Action-video-game+experience+alters+the+spatial+resolution+of+vision.">Action-video-game experience alters the spatial resolution of vision.</a> Psychological Science. 18, 88-94 (2007).</li><li>Hafed, Z. M., Clark, J. 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P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Maximum+likelihood+estimation:+the+best+PEST.">Maximum likelihood estimation: the best PEST.</a> Perception and Psychophysics. 28, 377-379 (1980).</li><li>Plaisted, K., Swettenham, J., Rees, L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Children+with+autism+show+local+precedence+in+a+divided+attention+task+and+global+precedence+in+a+selective+attention+task.">Children with autism show local precedence in a divided attention task and global precedence in a selective attention task.</a> Journal of Child Psychology and Psychiatry. 40, 733-742 (1999).</li><li>Posner, M. I. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Orienting+of+attention.">Orienting of attention.</a> Quarterly Journal of Experimental Psychology. 32, 3-25 (1980).</li><li>Smith, M. E., McEvoy, L. K., Gevins, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Neurophysiological+indices+of+strategy+development+and+skill+acquisition.">Neurophysiological indices of strategy development and skill acquisition.</a> Cognitive Brain Research. 7, 389-404 (1999).</li><li>St John, M., Kobus, D. A., Morrison, J. 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Talvez o obstáculo mais importante para os estudos de integração é o limite prático sobre a quantidade de tempo que um único sujeito experimental (especialmente um de uma população clínica) pode razoavelmente esperar para realizar antes de se tornar desgastado. Infelizmente, muitas vezes os mais controlada é um estímulo a partir do ponto do cientista de vista, a mais repetitiva e tediosa experimento pode parecer a partir do ponto do sujeito de vista. Pesquisas comportamentais em transtornos neuropsiquiátrico...

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		<th>Material Name</th>
		<th>Type</th>
		<th>Company</th>
		<th>Catalogue Number</th>
		<th>Comment</th>
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<td>128-channel BioSemi ActiveTwo measurement system</td>
<td>&nbsp;</td>
<td>BioSemi</td>
<td>&nbsp;</td>
<td><a href="http://www.biosemi.com">http://www.biosemi.com</a></td>
</tr>
<tr>
<td>32 channel A-set + CMS/DRL</td>
<td>&nbsp;</td>
<td>BioSemi</td>
<td>P32-ABC-ACMS</td>
<td>&nbsp;</td>
<tr>
<td>32 channel B-set</td>
<td>&nbsp;</td>
<td>BioSemi</td>
<td>P32-ABC-B</td>
<td>&nbsp;</td>
<tr>
<td>32 channel C-set</td>
<td>&nbsp;</td>
<td>BioSemi</td>
<td>P32-ABC-C</td>
<td>&nbsp;</td>
<tr>
<td>32 channel D-set</td>
<td>&nbsp;</td>
<td>BioSemi</td>
<td>P32-ABC-D</td>
<td>&nbsp;</td>
<tr>
<td>EX1-EX8 electrodes</td>
<td>&nbsp;</td>
<td>BioSemi</td>
<td>8 x TP PIN</td>
<td>&nbsp;</td>
<tr>
<td>128-channel cap</td>
<td>&nbsp;</td>
<td>BioSemi</td>
<td>CAP M 128</td>
<td>&nbsp;</td>
<tr>
<td>EyeLink 1000 infrared gaze tracker</td>
<td>&nbsp;</td>
<td>SR Research</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<tr>
<td>EyeLink 1000 Remote Camera Upgrade</td>
<td>&nbsp;</td>
<td>SR Research</td>
<td>n/a</td>
<td>Allows for target sticker tracking</td>
</tr>
<tr>
<td>SignaGel electrode gel</td>
<td>&nbsp;</td>
<td>Parker Labs</td>
<td>n/a</td>
<td>&nbsp;</td>
<tr>
<td>0.05% KCl electrolytic (NaCl) gel</td>
<td>&nbsp;</td>
<td>n/a</td>
<td>n/a</td>
<td>Purchased from compounding pharmacy</td>
</tr>
<tr>
<td>Intensity Pro</td>
<td>&nbsp;</td>
<td>Blackmagic Design</td>
<td>&nbsp;</td>
<td>&nbsp;</td>		</tbody>
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combining computer game-based behavioural experiments with high-density eeg and infrared gaze tracking

Paradigmas experimentais são valiosos na medida em que o tempo e outros parâmetros de seus estímulos são bem especificado e controlado, e na medida em que o rendimento de dados relevantes para o processamento cognitivo que ocorre sob condições ecologicamente válido. Esses dois objetivos, muitas vezes estão em desacordo, uma vez que estímulos bem controlada, muitas vezes são muito repetitivas para manter a motivação dos sujeitos. Estudos empregando eletroencefalografia (EEG) são muitas vezes especialmente sensíveis a este dilema entre validade ecológica e controle experimental: alcançar suficiente sinal-ruído em médias demandas fisiológicas grande número de ensaios repetidos dentro de longas sessões de gravação, limitando a piscina sujeitos a indivíduos com a capacidade e paciência para executar uma tarefa definida uma e outra vez. Essa restrição limita severamente a capacidade dos pesquisadores para investigar as populações mais jovens, bem como populações clínicas associadas com a ansiedade elevada ou anormalidades de atenção. Mesmo adulto, sujeitos não-clínicos podem não ser capazes de alcançar seus níveis típicos de desempenho ou envolvimento cognitivo: um sujeito desmotivado para quem uma tarefa experimental é pouco mais do que uma tarefa não é o mesmo, comportamental, cognitiva ou neuralmente, como um sujeito que está intrinsecamente motivado e comprometido com a tarefa. Um crescente corpo de literatura demonstra que a incorporação de experiências nos jogos de vídeo pode fornecer um caminho entre as pontas desse dilema entre o controle experimental e validade ecológica. A narrativa de um jogo fornece um contexto mais realista em que as tarefas ocorrem, melhorando a sua validade ecológica (Chaytor &amp; Schmitter-Edgecombe, 2003). Além disso, neste contexto fornece motivação para completar tarefas. No nosso jogo, os indivíduos executam várias missões para coletar recursos, afastar os piratas, comunicações interceptar ou facilitar as relações diplomáticas. Ao fazê-lo, eles também realizam uma série de tarefas cognitivas, incluindo um paradigma Posner atenção-shifting (Posner, 1980), um go / no-go teste de motor de inibição, uma tarefa psicofísica movimento limiar coerência, o Embedded Figures Test (Witkin , 1950, 1954) e uma teoria da mente (Wimmer &amp; Perner, 1983) tarefa. O software do jogo registra automaticamente estímulos jogo e as ações dos indivíduos e as respostas em um arquivo de log, e envia códigos de eventos para sincronizar com gravadores de dados fisiológicos. Assim o jogo pode ser combinado com medidas fisiológicas, tais como EEG, ou fMRI, e com a cada momento de rastreamento do olhar. Rastreamento de olhar pode verificar o cumprimento dos indivíduos com tarefas comportamentais (fixação, por exemplo) e atenção explícita aos estímulos experimentais, e também excitação fisiológica que se reflectem no dilatação da pupila (Bradley et al., 2008). Na grande frequências de amostragem suficiente, rastreamento olhar também pode ajudar a avaliar a atenção secreta que se reflectem no microsaccades - movimentos oculares, que são pequenos demais para foveate um novo objeto, mas são tão rápidos no início e têm a mesma relação entre a distância angular e velocidade de pico como fazer sacadas que atravessam grandes distâncias. A distribuição das direções de microsaccades correlaciona-se com a direção (não) secreto de atenção (Hafed &amp; Clark, 2002).

Watch this Scientific Journal Video about Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking at JoVE.com

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking

Procedimentos para gravação de alta densidade de dados EEG e olhar durante o jogo de computador baseado em tarefas cognitivas são descritos. Usando um videogame para apresentar tarefas cognitivas aumenta a validade ecológica sem sacrificar o controle experimental.

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We use magnetoencephalography (MEG) and electroencephalography (EEG) to locate and determine the temporal evolution in brain areas involved in the ...

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Evento relacionados com alta densidade de Aquisição de Dados Potencial em Neurociência Cognitiva

Functional magnetic resonance imaging (fMRI) is currently the standard method of evaluating brain function in the field of Cognitive Neuroscience, in part ...

High-density EEG Recordings of the Freely Moving Mice using Polyimide-based Microelectrode

Gravações de alta densidade EEG dos Ratos movimentando-se livremente usando Polyimide baseado microeletrodos

Electroencephalogram (EEG) indicates the averaged electrical activity of the neuronal populations on a large-scale level. It is widely utilized as a ...

Recording Large-scale Neuronal Ensembles with Silicon Probes in the Anesthetized Rat

Gravação em grande escala Ensembles Neuronal com Sondas Silício na rato anestesiado

Large scale electrophysiological recordings from neuronal ensembles offer the opportunity to investigate how the brain orchestrates the wide variety of ...

Visualizing the Effects of a Positive Early Experience, Tactile Stimulation, on Dendritic Morphology and Synaptic Connectivity with Golgi-Cox Staining

Visualizar os Efeitos de uma experiência precoce positiva, Tátil Estimulação, em dendríticas Morfologia e Synaptic conectividade com Golgi-Cox Coloração

To generate longer-term changes in behavior, experiences must be producing stable changes in neuronal morphology and synaptic connectivity. Tactile ...

Olfactory Behaviors Assayed by Computer Tracking Of Drosophila in a Four-quadrant Olfactometer

Olfactory Behaviors Assayed by Computer Tracking Of Drosophila in a Four-quadrant Olfactometer

Comportamentos olfativos ensaiadas pelo monitoramento do computador de<em&gt; Drosophila</em&gt; Em um olfatômetro de quatro quadrantes

A key challenge in neurobiology is to understand how neural circuits function to guide appropriate animal behaviors. Drosophila melanogaster is an ...

Visual Evoked Potential Recordings in Mice Using a Dry Non-invasive Multi-channel Scalp EEG Sensor

Gravações de potenciais evocadas visuais em ratos usando um não-invasivo seco multi-canal do couro cabeludo Sensor de EEG

For scalp EEG research environments with laboratory mice, we designed a dry-type 16 channel EEG sensor which is non-invasive, deformable, and re-usable ...

Analyzing Neural Activity and Connectivity Using Intracranial EEG Data with SPM Software

Analisando a atividade Neural e conectividade usando dados de EEG intracraniano com SPM Software

Measuring neural activity and connectivity associated with cognitive functions at high spatial and temporal resolutions is an important goal in cognitive ...

Conducting Hyperscanning Experiments with Functional Near-Infrared Spectroscopy

Hyperscanning experimentos com espectroscopia de infravermelho próximo funcional

Concurrent brain recordings of two or more interacting persons, an approach termed hyperscanning, are gaining increasing importance for our understanding ...

Lipid Bilayer Experiments with Contact Bubble Bilayers for Patch-Clampers

Experimentos de bicamada lipídica com contato bolha Bilayers para Patch-Clampers

Lipid bilayers provide a unique experimental platform for functional studies of ion channels, allowing the examination of channel-membrane interactions ...