Name: normothermic cardiac arrest and cardiopulmonary resuscitation: a mouse model of ischemia-reperfusion injury
Uploaded: 2011-08-30T12:00:00
Description: Watch this Scientific Journal Video about Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury at JoVE.com

설명된 모든 절차가 연구와 모든 동물의 프로토콜은 오레곤 보건 과학 대학 기관 애니멀 케어 및 사용위원회에 의해 승인된 동물의 보호 및 사용에 대한 건강 가이드 국립 연구소에 따라 실시하고 있습니다. 1. 수술 준비 <ol><li> 마우스의 무게를. 설명한 절차는 G. 20 ~ 25 무게 C57BL / 6 생쥐에서 수행됩니다 마취는 isoflurane 3-4%를 사용하여 유도 상자에 유도하고, 이후 공기 / 산?...

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마우스에서 심장 마비와 심폐 소생의 normothermic 모델 아키 전체 - 바디 hypoperfusion의 가장 흔한 임상 원인의 pathophysiology과 형태를 복제 모델의 평가의 여러 아베를 제공합니다. 가설 테스트는 유전자 조작 기술과 잘 이해하고 특징 해부학 및 실험실 마우스 생리학의 갑옷의 한 벌에 액세스하여 주었 수 있습니다. 여기에 설명한 바와 같이, 경험 손에 생존이 80 %입니다. 수술 준?...

<table border="1"><tbody><tr><th> 시약의 이름 </th><th> 회사 </th><th> 카탈로그 번호 </th></tr><tr><td> 염화칼륨 </td><td> 애보트 의료 </td><td> 06653-5 </td></tr><tr><td> Isoflurane </td><td> 애보트 의료 </td><td> 05260-05 (및 기타) </td></tr><tr><td> 에피네프린 HCL </td><td> 복수 </td><td> 복수 </td></tr><tr><td> Digi - 감지 온도 컨트롤러 </td><td> 콜 - 파머 </td><td> EW - 89000-00 </td></tr><tr><td> Angiocath IV 캐스 </td><td> VWR </td><td> 381134 </td></tr><tr><td> Frova 직각기도 introducer </td><td> 요리사 </td><td> G27282 </td></tr><tr><td> 마우스에 대한 MicroVent 환풍기 </td><td> 하버드 장치 </td><td> 733591 </td></tr></tbody></table>

normothermic cardiac arrest and cardiopulmonary resuscitation: a mouse model of ischemia-reperfusion injury

급성 신장 상해 (아키)는 높은 사망률 1-4과 가장 자주 전체 - 바디 hypoperfusion로 인해이 중요한 질병의 일반적인, 매우 치명적인, 복잡합니다. 설치류 모델에서 전체 - 몸 hypoperfusion의 5,6 성공적인 복제 어려움이 따른 다네되었습니다. 초점 국소 빈혈을 채용 7-9,9,10 모델은 반복적으로 임상 설정하고, 유전자 조작의 전체 도구 모음에 온 몸이 hypoperfusion의 부족 액세스를 허용 큰 동물 모델로 번역하지 검색 결과를 보여준 마우스 가능. 11,12 그러나, 최근에 심장 마비와 심폐 소생의 마우스 모델은 모델 아키 적응시킬 수있는 부상했다. 13이 모델은 안정적으로 임상 아키에서 본 physiologic, 기능 해부학, 그리고 histologic 결과를 재현 , 빠르게 반복하고, 유전자 조작 기술, 대형 동물 저렴한 비용으로 상대하고, 사용의 용이성에 대한 액세스 권한을 포함하여 murine 수술 모델의 중요한 장점을 모두 제공합니다. 우리 그룹은 아키의 기관 특정 결과의 숫자를 평가하기 위해이 모델의 사용 경험을 개발했습니다. 14,15

Watch this Scientific Journal Video about Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury at JoVE.com

Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury

perioperative 그리고 중요한 치료 관련 급성 신장 손상에 대한 강력한 모델이 제공됩니다. 그것이 거의 임상 아키의 histologic 및 기능 변경 내용을 복제할 수 있습니다 심장 마비에 의해 유도 온 몸이 hypoperfusion을 사용합니다.

Normothermic 심장 마비와 심폐 소생술의 : 국소 빈혈 - Reperfusion 상해의 마우스 모델

Acute Kidney Injury (AKI) is a common, highly lethal, complication of critical illness which has a high mortality1-4 and which is most 
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Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice

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Ischemia-reperfusion induced acute kidney injury (IR-AKI) is widely used as a model of AKI in mice, but results are often quite variable with high, often ...

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Induction and Assessment of Ischemia-reperfusion Injury in Langendorff-perfused Rat Hearts

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면역 반응의 생체 내에 다중 광자 이미징을위한 마우스 귀 피부에 유도 허혈 - 재관류 손상

Ischemia-reperfusion injury (IRI) occurs when there is transient hypoxia due to the obstruction of blood flow (ischemia) followed by a subsequent ...

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The US-CAB (Ultrasound, Circulation/Airway/Breathing) protocol integrates several sonographic techniques into a structured assessment of the circulation, ...

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Ischemia-reperfusion injury is the main cause of flap failure in reconstructive microsurgery. The rat is the preferred preclinical animal model in many ...

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model

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Orthotopic liver transplantation (OLT) in rats is a tried and proven animal model used for preoperative, intraoperative, and postoperative studies, ...

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