Name: correlating behavioral responses to fmri signals from human prefrontal cortex: examining cognitive processes using task analysis
Uploaded: 2012-06-20T12:00:00
Description: Watch this Scientific Journal Video about Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis at JoVE.com

由国家科学和工程研究理事会（NSERC），卫生，纽约大学和作者系JFXD资​​助等博士资金由安大略问题赌博研究中心（OPGRC）。

1。进入磁共振室<ol><li>参与者完成一份同意书，解释所有的实验的风险（如心脏起搏器，幽闭恐惧症，金属植入物，怀孕的机会等），和他们的参与利益。 </li><li>所有的参与者都需要填写的MRI安全和筛选问卷（简要病史，以往的手术禁忌等）参加者必须排除。 </li></ol> 2。任务概述和培训<ol><li>反扫视任务性能提供培训。 <ol><li>绿色固定表明亲扫视审判。指示与会者在8-10°的?...

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	<li>Stroop, J. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Studies+of+interference+in+serial+verbal+reactions.">Studies of interference in serial verbal reactions.</a> Journal of Experimental Psychology. 18, 643-662 (1935).</li><li>Ovaysikia, S., Tahir, K. A., Chan, J. L., DeSouza, J. F. X. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Word+wins+over+face:+emotional+Stroop+effect+activates+the+frontal+cortical+network.">Word wins over face: emotional Stroop effect activates the frontal cortical network.</a> Front Hum. Neurosci. 4, 234 (2011).</li><li>Hallett, P. E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Primary+and+secondary+saccades+to+goals+defined+by+instructions.">Primary and secondary saccades to goals defined by instructions.</a> Vision Res. 18, 1279-1296 (1978).</li><li>Connolly, J. D., Goodale, M. A., DeSouza, J. F. X., Menon, R. S., Vilis, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+comparison+of+frontoparietal+fMRI+activation+during+anti-saccades+and+anti-pointing.">A comparison of frontoparietal fMRI activation during anti-saccades and anti-pointing.</a> J. Neurophysiol. 84, 1645-1655 (2000).</li><li>DeSouza, J. F. X., Menon, R. S., Everling, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Preparatory+set+associated+with+pro-saccades+and+anti-saccades+in+humans+investigated+with+event-related+FMRI.">Preparatory set associated with pro-saccades and anti-saccades in humans investigated with event-related FMRI.</a> J. Neurophysiol. 89, 1016-1023 (2003).</li><li>Everling, S., DeSouza, J. F. X. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Rule-dependent+activity+for+prosaccades+and+antisaccades+in+the+primate+prefrontal+cortex.">Rule-dependent activity for prosaccades and antisaccades in the primate prefrontal cortex.</a> J. Cogn. Neurosci. 17, 1483-1496 (2005).</li><li>Ford, K. A., Goltz, H. C., Brown, M. R. G., Everling, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Neural+processes+associated+with+antisaccade+task+performance+investigated+with+event-related+fMRI.">Neural processes associated with antisaccade task performance investigated with event-related fMRI.</a> J. Neurophysiol. 94, 429-440 (2005).</li><li>DeSouza, J. F. X., Nicolle, D. A., Vilis, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Task-dependent+changes+in+the+shape+and+thickness+of+Listing's+plane.">Task-dependent changes in the shape and thickness of Listing's plane.</a> Vision Res. 37, 2271-2282 (1997).</li><li>Hadjikhani, N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Mechanisms+of+migraine+aura+revealed+by+functional+MRI+in+human+visual+cortex.">Mechanisms of migraine aura revealed by functional MRI in human visual cortex.</a> Proc. Natl. Acad. Sci. U.S.A. 98, 4687-4692 (2001).</li><li>DeSouza, J. F. X. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Eye+position+signal+modulates+a+human+parietal+pointing+region+during+memory-guided+movements.">Eye position signal modulates a human parietal pointing region during memory-guided movements.</a> J. Neurosci. 20, 5835-5840 (2000).</li></ol>

确定大脑区域依赖于扫描的任务（即不一致与全等的情绪和面部表情的Stroop效应;或反扫视与亲扫视）之间建立一个准确的对比度，以产生一个激活地图相关任务。这些功能的地图，可以更精细的扫描器收集行为主体作出错误的删除试验。这些错误可以被删除，如果有足够数量比功能地图的错误可以作出这些3,4,5,6。最重要的是，当研究Stroop任务不一致的任务，有较长的反应时间，反应时间...

A correction was made to <a href="http://http://www.jove.com/video/3237">Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis</a>. Joseph DeSouza and Laura Pynn middle initials were omitted at publication.
These have been corrected to:
Joseph F.X. DeSouza Laura K. Pynn

A correction was made to <a href="http://http://www.jove.com/video/3237">Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis</a>. Some of the authors middle initials were omitted.

Erratum: Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

<table border="1"><tbody><tr><td> 设备名称 </td><td> 公司 </td></tr><tr><td> 3特斯拉的核磁共振机</td><td>西门子MAGNETOM三重奏（德国埃尔兰根） </td></tr><tr><td> iViewX眼跟踪</td><td> SensoMotoric仪器公司</td></tr><tr><td> BrainVoyager群星软件</td><td>脑创新，荷兰马斯特里赫特</td></tr><tr><td>四按钮游戏杆</td><td>目前的设计公司，费城宾夕法尼亚，美国</td></tr></tbody></table> 表1。特定的试剂和设备。

correlating behavioral responses to fmri signals from human prefrontal cortex: examining cognitive processes using task analysis

这种方法文件的目的是描述如何实现影像学技术研究互补从事大脑由两个类似的任务。然后，可以参加“期间任务的功能磁共振成像扫描仪的性能行为相关的大脑活动使用的血氧水平依赖信号。我们衡量行为能够排序正确的试验，主体正确地执行任务，然后才能研究大脑的信号与纠正性能。反之，如果对象不执行任务的正确，这些试验是在同样的分析与正确的试验，我们将介绍，不仅是正确的性能试验。因此，在许多情况下，这些错误可以用自己的，然后关联到他们的大脑活动。我们描述了两个相辅相成的任务，在我们的实验室用于检查在一个自动应答的抑制大脑的Stroop 1和反扫视任务。 “情绪Stroop范式指示参与者报告的叠加的情绪整个情感面或面部的表情的脸刺激1,2&#39;字&#39;。当字和表情是指以不同的情绪，两者之间的冲突必须说，什么是自动读取发生。参与者要解决两个同时竞争的过程读字和面部表情之间的冲突。我们读出一个字的冲动，导致强烈的“刺激 - 反应（SR）的协会，从而抑制这些强SR的困难和参与者都容易犯错误。克服这种冲突和指导注意力从脸上或字，需要受到抑制过程通常指示注意更加突出的刺激的​​底部。同样，在反扫视任务3,4,5,6，其中一个指令提示是用来指示只注意外围的刺激位置，但在EY将é运动镜相反的立场。然而，我们再次测量分拣到正确的和错误的审判行为反应，然后可以与大脑活动的参与者允许通过记录眼球运动的行为。现在影像学，使研究人员能够测量不同的行为，正确的和错误的审判，不同的认知过程的指标，并查明涉及不同的神经网络。

Watch this Scientific Journal Video about Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis at JoVE.com

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

我们的研究目标是大脑活动的相关行为。准确的行为的措施和成像技术，让我们澄清脑 - 行为之间的关系。

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