B7-H1（PD-L1）免疫组化染色石蜡的嵌入式幻灯片的胰腺癌组织
January 3rd, 2013
•Elaine Bigelow1,2, Katherine M. Bever1,2, Haiying Xu1,2,3, Allison Yager1, Annie Wu1,2,4, Janis Taube3,5, Lieping Chen6, Elizabeth M. Jaffee1,2,5,7,8, Robert A. Anders1,2,5,8, Lei Zheng1,2,4,5,7
1The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 2Department of Oncology, The Johns Hopkins University School of Medicine, 3Department of Dermatology, The Johns Hopkins University School of Medicine, 4Department of Surgery, Johns Hopkins University School of Medicine, 5The Sol Goldman Pancreatic Cancer Center, The Johns Hopkins University School of Medicine, 6Yale Cancer Center, Yale School of Medicine, 7The Skip Viragh Center for Pancreatic Cancer, The Johns Hopkins University School of Medicine, 8Department of Pathology, The Johns Hopkins University School of Medicine
B7-H1（PD-L1）和PD-1的结合提供了重要的肿瘤引起的免疫抑制肿瘤的微环境中的信号。免疫组织化学技术的特点B7-H1在胰腺癌组织中的表达和定位的描述。
Tags
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved