अग्नाशय के Adenocarcinoma ऊतक B7-H1 immunohistochemical धुंधला (पीडी L1) आयल एम्बेडेड स्लाइड्स
January 3rd, 2013
•Elaine Bigelow1,2, Katherine M. Bever1,2, Haiying Xu1,2,3, Allison Yager1, Annie Wu1,2,4, Janis Taube3,5, Lieping Chen6, Elizabeth M. Jaffee1,2,5,7,8, Robert A. Anders1,2,5,8, Lei Zheng1,2,4,5,7
1The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 2Department of Oncology, The Johns Hopkins University School of Medicine, 3Department of Dermatology, The Johns Hopkins University School of Medicine, 4Department of Surgery, Johns Hopkins University School of Medicine, 5The Sol Goldman Pancreatic Cancer Center, The Johns Hopkins University School of Medicine, 6Yale Cancer Center, Yale School of Medicine, 7The Skip Viragh Center for Pancreatic Cancer, The Johns Hopkins University School of Medicine, 8Department of Pathology, The Johns Hopkins University School of Medicine
B7-H1 (पी.डी. L1) और उसके PD-1 के लिए बाध्य एक प्रमुख ट्यूमर प्रेरित ट्यूमर microenvironment में immunosuppressive संकेत प्रदान करते हैं. एक immunohistochemical धुंधला अभिव्यक्ति और अग्नाशय ग्रंथिकर्कटता में B7-H1 का स्थानीयकरण विशेषताएँ तकनीक वर्णित है यहाँ.
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