Name: mapping cortical dynamics using simultaneous meg/eeg and anatomically-constrained minimum-norm estimates: an auditory attention example
Uploaded: 2012-10-24T13:00:00
Description: Watch this Scientific Journal Video about Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example at JoVE.com

लेखकों के लिए उनके सहायक टिप्पणियों के लिए धन्यवाद देना चाहूंगा Matti एस Hämäläinen, Lilla Zöllei और तीन गुमनाम समीक्षक. धन स्रोतों: R00DC010196 (AKCL); T32DC000018 (EDL); T32DC005361 (रूट).

1. संरचनात्मक डाटा अधिग्रहण और प्रसंस्करण <ol><li> एक आकर्षण संस्कार से तैयार तेजी से ढाल गूंज (MPRAGE) इस विषय के एमआरआई स्कैन मोल. यह जो विशिष्ट स्कैनिंग प्रोटोकॉल का उपयोग किया जाता है के आधार पर 5-10 मिनट लग सकत?...

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आदेश में हासिल कर ली एमईजी / ईईजी डेटा से प्रांतस्था पर द्विध्रुवीय सक्रियण का अनुमान लगाने के लिए, हम एक व्युत्क्रम समस्या है, जो एक अद्वितीय स्थायी समाधान नहीं है जब तक उचित और anatomically और physiologically ध्वनि बाधा...

<table border="1"><tbody><tr><td> उपकरण / सॉफ्टवेयर का नाम </td><td> कंपनी / स्रोत </td><td></td><td></td></tr><tr><td> 306-चैनल Vectorview एमईजी प्रणाली </td><td> लिमिटेड Eleka - Neuromag, </td><td></td><td></td></tr><tr><td> 1.5-टी Avanto एमआरआई स्कैनर </td><td> सीमेंस चिकित्सा समाधान </td><td></td><td></td></tr><tr><td> FreeSurfer </td><td></td><td></td><td> <a href="http://freesurfer.net/" target="_blank">http://freesurfer.net/</a> </td></tr><tr><td> MNE सॉफ्टवेयर </td><td></td><td></td><td> <a href="http://www.nmr.mgh.harvard.edu/martinos/userInfo/data/sofMNE.php" target="_blank">http://www.nmr.mgh.harvard.edu/martinos/userInfo/data/sofMNE.php</a> </td></tr><tr><td> ईईजी इलेक्ट्रोड </td><td> ब्रेन उत्पाद, Easycap GmbH </td><td></td><td></td></tr><tr><td> 3Space Fastrak प्रणाली </td><td> Polhemus </td><td></td><td></td></tr><tr><td> ऑप्टिकल बटन बॉक्स (एफआईयू - 932) </td><td> वर्तमान डिजाइन </td><td></td><td></td></tr></tbody></table>

mapping cortical dynamics using simultaneous meg/eeg and anatomically-constrained minimum-norm estimates: an auditory attention example

Magneto- and electroencephalography (MEG/EEG) are neuroimaging techniques that provide a high temporal resolution particularly suitable to investigate the cortical networks involved in dynamical perceptual and cognitive tasks, such as attending to different sounds in a cocktail party. Many past studies have employed data recorded at the sensor level only, i.e., the magnetic fields or the electric potentials recorded outside and on the scalp, and have usually focused on activity that is time-locked to the stimulus presentation. This type of event-related field / potential analysis is particularly useful when there are only a small number of distinct dipolar patterns that can be isolated and identified in space and time. Alternatively, by utilizing anatomical information, these distinct field patterns can be localized as current sources on the cortex. However, for a more sustained response that may not be time-locked to a specific stimulus (e.g., in preparation for listening to one of the two simultaneously presented spoken digits based on the cued auditory feature) or may be distributed across multiple spatial locations unknown a priori, the recruitment of a distributed cortical network may not be adequately captured by using a limited number of focal sources.
Here, we describe a procedure that employs individual anatomical MRI data to establish a relationship between the sensor information and the dipole activation on the cortex through the use of minimum-norm estimates (MNE). This inverse imaging approach provides us a tool for distributed source analysis. For illustrative purposes, we will describe all procedures using FreeSurfer and MNE software, both freely available. We will summarize the MRI sequences and analysis steps required to produce a forward model that enables us to relate the expected field pattern caused by the dipoles distributed on the cortex onto the M/EEG sensors. Next, we will step through the necessary processes that facilitate us in denoising the sensor data from environmental and physiological contaminants. We will then outline the procedure for combining and mapping MEG/EEG sensor data onto the cortical space, thereby producing a family of time-series of cortical dipole activation on the brain surface (or "brain movies") related to each experimental condition. Finally, we will highlight a few statistical techniques that enable us to make scientific inference across a subject population (i.e., perform group-level analysis) based on a common cortical coordinate space.

Watch this Scientific Journal Video about Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example at JoVE.com

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

हम चुंबक और (एमईजी / ईईजी) Electroencephalography, संरचनात्मक चुंबकीय अनुनाद इमेजिंग (एमआरआई) के द्वारा कब्जा कर लिया जानकारी के साथ संयुक्त, cortical श्रवण ध्यान के साथ जुड़े नेटवर्क की गतिशीलता नक्शा करने के लिए उपयोग.

मानचित्रण Cortical युगपत एमईजी / ईईजी और Anatomically विवश न्यूनतम आदर्श अनुमान का उपयोग गतिशीलता: एक श्रवण ध्यान उदाहरण

Magneto- and electroencephalography (MEG/EEG) are neuroimaging techniques that provide a high temporal resolution particularly suitable to investigate the ...

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Neuroscience

Functional Mapping with Simultaneous MEG and EEG

एक साथ एमईजी और ईईजी के साथ कार्यात्मक मानचित्रण

We use magnetoencephalography (MEG) and electroencephalography (EEG) to locate and determine the temporal evolution in brain areas involved in the ...

Preparation and Culture of Chicken Auditory Brainstem Slices

तैयारी और चिकन श्रवण brainstem स्लाइस की संस्कृति

The chicken auditory brainstem is a well-established model system that has been widely used to study the anatomy and physiology of auditory processing at ...

Recording Human Electrocorticographic (ECoG) Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Recording Human Electrocorticographic ECoG Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Neuroscientific अनुसंधान और वास्तविक समय कार्यात्मक cortical मानचित्रण के लिए मानव Electrocorticographic सिग्नल (ECOG) रिकॉर्डिंग

Neuroimaging studies of human cognitive, sensory, and motor processes are usually based on noninvasive techniques such as electroencephalography (EEG), ...

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

उच्च क्षेत्र fMRI का उपयोग वयस्क बिल्लियों में श्रवण प्रांतस्था के कार्यात्मक इमेजिंग

Current knowledge of sensory processing in the mammalian auditory system is mainly derived from electrophysiological studies in a variety of animal ...

Optogenetic Stimulation of the Auditory Nerve

श्रवण तंत्रिका की optogenetic उत्तेजना

Direct electrical stimulation of spiral ganglion neurons (SGNs) by cochlear implants (CIs) enables open speech comprehension in the majority of implanted ...

Touchscreen Sustained Attention Task (SAT) for Rats

Touchscreen Sustained Attention Task SAT for Rats

चूहों के लिए टचस्क्रीन निरंतर ध्यान कार्य (सैट)

Sustained attention is the ability to monitor intermittent and unpredictable events over a prolonged period of time. This attentional process subserves ...

Simultaneous Recordings of Cortical Local Field Potentials, Electrocardiogram, Electromyogram, and Breathing Rhythm from a Freely Moving Rat

एक स्वतंत्र रूप से चलती चूहे से Cortical स्थानीय क्षेत्र क्षमता, इलेक्ट्रोकार्डियोग्राम, Electromyogram, और श्वास लय के एक साथ रिकॉर्डिंग

Monitoring the physiological dynamics of the brain and peripheral tissues is necessary for addressing a number of questions about how the brain controls ...

Visualization of Motor Axon Navigation and Quantification of Axon Arborization In Mouse Embryos Using Light Sheet Fluorescence Microscopy

मोटर Axon नेविगेशन और माउस के ठहराव में Axon Arborization के दृश्य प्रकाश शीट प्रतिदीप्ति माइक्रोस्कोपी का प्रयोग भ्रूण

Spinal motor neurons (MNs) extend their axons to communicate with their innervating targets, thereby controlling movement and complex tasks in ...

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines

प्रो-भड़काऊ साइटोकिन्स के इंट्रासैरेब्रल इंजेक्शन द्वारा प्रेरित व्यापक सेरेब्रल कॉर्टिकल डेमिलिनेशन का चूहा मॉडल

Multiple sclerosis (MS) is the most common immune-mediated disease of the central nervous system (CNS) and progressively leads to physical disability and ...

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

गैर-आक्रामक इलेक्ट्रोएन्सेफेलोग्राम का उपयोग करके कॉर्टिकल कनेक्टिविटी का सांख्यिकीय मॉडलिंग

Non-invasive electrophysiological recordings are useful for the evaluation of nervous system function. These techniques are inexpensive, fast, replicable, ...