Name: minimal erythema dose (med) testing
Uploaded: 2013-05-28T12:00:00
Description: Watch this Scientific Journal Video about Minimal Erythema Dose MED Testing at JoVE.com

这个工作是由R21CA134819（CH）T32CA009035的（SD），P30CA006927（癌症中心的核心格兰特）。笔者想感谢伊丽莎白Culnan为她的协助与参与招聘，利亚博伊尔，伊娃帕尼格拉希，他们协助程序的开发和凯特·梅内塞斯和Jeanne Pomenti的稿件准备与她的协助。我们也感谢期刊审稿的宝贵建议。

1。准备UV曝光<ol><li>解释如何MED测试工作的参与者（“我要你的胳膊上露出一些皮肤在紫外线照射下的过程约20分钟，明天，我们要检查你的皮肤的部分，以确定你是多么敏感的光，您可能会遇到一个小区域，我们暴露在紫外线晒伤，如果晒伤的痛苦或困扰你，你可以把它像任何其他晒伤“。） </li><li>工作人员和参与者应戴防紫外线眼镜。 </li><li>参与者应穿着一件短袖衬衫或卷起她的袖子。 </l...

<ol>
	<li>Fitzpatrick, T. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+validity+and+practicality+of+sun-reactive+skin+types+I+through+VI.">The validity and practicality of sun-reactive skin types I through VI.</a> Archives of Dermatology. 124, 869-871 (1988).</li><li>Bodekaer, M., Akerstrom, U., Wulf, H. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Accumulation+of+sunscreen+in+human+skin+after+daily+applications:+a+study+of+sunscreens+with+different+ultraviolet+radiation+filters.">Accumulation of sunscreen in human skin after daily applications: a study of sunscreens with different ultraviolet radiation filters.</a> Photodermatol. Photoimmunol. Photomed. 28, 127-132 (2012).</li><li>Kwon, I. H., Kwon, H. H., Na, S. J., Youn, J. I. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Could+colorimetric+method+replace+the+individual+minimal+erythemal+dose+(MED)+measurements+in+determining+the+initial+dose+of+narrow-band+UVB+treatment+for+psoriasis+patients+with+skin+phototype+III-V?.">Could colorimetric method replace the individual minimal erythemal dose (MED) measurements in determining the initial dose of narrow-band UVB treatment for psoriasis patients with skin phototype III-V?.</a> J. Eur. Acad. Dermatol. Venereol. , (2012).</li><li>Youn, J. I., Park, J. Y., Jo, S. J., Rim, J. H., Choe, Y. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Assessment+of+the+usefulness+of+skin+phototype+and+skin+color+as+the+parameter+of+cutaneous+narrow+band+UVB+sensitivity+in+psoriasis+patients.">Assessment of the usefulness of skin phototype and skin color as the parameter of cutaneous narrow band UVB sensitivity in psoriasis patients.</a> Photodermatol. Photoimmunol. Photomed. 19, 261-264 (2003).</li><li>Henriksen, M., Na, R., Agren, M. S., Wulf, H. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Minimal+erythema+dose+after+multiple+UV+exposures+depends+on+pre-exposure+skin+pigmentation.">Minimal erythema dose after multiple UV exposures depends on pre-exposure skin pigmentation.</a> Photodermatol. Photoimmunol. Photomed. 20, 163-169 (2004).</li><li>Kraemer, C. K., Menegon, D. B., Cestari, T. F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Determination+of+the+minimal+phototoxic+dose+and+colorimetry+in+psoralen+plus+ultraviolet+A+radiation+therapy.">Determination of the minimal phototoxic dose and colorimetry in psoralen plus ultraviolet A radiation therapy.</a> Photodermatol. Photoimmunol. Photomed. 21, 242-248 (2005).</li><li>Sachdeva, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Fitzpatrick+skin+typing:+applications+in+dermatology.">Fitzpatrick skin typing: applications in dermatology.</a> Indian J. Dermatol. Venereol. Leprol. 75, 93-96 (2009).</li><li>Webb, A. R., Kift, R., Berry, J. L., Rhodes, L. E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+vitamin+D+debate:+translating+controlled+experiments+into+reality+for+human+sun+exposure+times.">The vitamin D debate: translating controlled experiments into reality for human sun exposure times.</a> Photochem. Photobiol. 87, 741-745 (2011).</li><li>Otman, S. G., Edwards, C., Gambles, B., Anstey, A. V. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Validation+of+a+semiautomated+method+of+minimal+erythema+dose+testing+for+narrowband+ultraviolet+B+phototherapy.">Validation of a semiautomated method of minimal erythema dose testing for narrowband ultraviolet B phototherapy.</a> Br. J. Dermatol. 155, 416-421 (2006).</li><li>Taylor, D. K., Anstey, A. V., Coleman, A. J., Diffey, B. L., Farr, P. M., Ferguson, S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Guidelines+for+dosimetry+and+calibration+in+ultraviolet+radiation+therapy:+a+report+of+a+British+Photodermatology+Group+workshop.">Guidelines for dosimetry and calibration in ultraviolet radiation therapy: a report of a British Photodermatology Group workshop.</a> Br. J. Dermatol. 146, 755-763 (2002).</li></ol>

紫外辐射（UV）疗法有时被用来作为一种治疗各种常见的皮肤状况，包括牛皮癣，痤疮和湿疹。 UV光的剂量是根据个人的皮肤敏感性，作为个人的帕特里克皮肤类型的函数被确定的规定的奴才通过VI（非常公平很暗）。2人类皮肤的变化在其对紫外线辐射的敏感度因为不同程度的皮肤色素沉着，厚度，以及其他因素。因此，建立适当的剂量的UV光，给予患者，患者有时筛选，以确定一个最小?...

minimal erythema dose (med) testing

紫外辐射（UV）疗法有时被用来作为一种治疗各种常见的皮肤状况，包括牛皮癣，痤疮和湿疹。 UV光的剂量是规定根据个人的皮肤敏感性。因此，建立适当的剂量的UV光，给予患者，患者有时筛选以确定最小红斑量（MED），这是紫外线辐射的量，将产生最小红斑（晒伤或发红引起的充血毛细血管）一个人的皮肤接触后在几个小时内。本文介绍了如何进行最小红斑量（MED）测试。目前还没有简单的方法来确定一个合适的紫外线剂量用于临床或研究目的，而不进行正式MED测试，需要观察小时后测试，或非正式的试验和错误测试剂量不足或过度的风险。然而，一些替代的方法进行了讨论。

<img alt="图1" fo:content-width="4in" fo:src="/files/ftp_upload/50175/50175fig1highres.jpg" src="/files/ftp_upload/50175/50175fig1.jpg" /> 图1。四个步骤进行MED测试：准备进行紫外线照射，紫外线的照射，评估的MED，确定的MED。 <img alt="图2" src="/files/ftp_upload/50175/50175fig2.jpg" /><p class...

Watch this Scientific Journal Video about Minimal Erythema Dose MED Testing at JoVE.com

Minimal Erythema Dose MED Testing

本文介绍了如何进行最小红斑量（MED）测试，以确定最低剂量的紫外线辐射会引起红斑（燃烧）时，给予个体。

最小红斑剂量（MED）测试

Ultraviolet radiation (UV) therapy is  sometimes used as a treatment for various common skin conditions, including  psoriasis, acne, and eczema. The ...

Research

JoVE Journal

Medicine

Minimal Erythema Dose (MED) Testing

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Precision Implementation of Minimal Erythema Dose (MED) Testing to Assess Individual Variation in Human Inflammatory Response

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