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In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis

DOI :

10.3791/50296-v

October 20th, 2013

October 20th, 2013

9,159 Views

1Department of Radiology, University Hospital of Strasbourg, 2EA 3432, University of Strasbourg, 3Department of Bacteriology, University Hospital of Strasbourg

We demonstrate how to perform macrophage MR imaging using ultrasmall superparamagnetic contrast agent (USPIO) in septic arthritis, allowing an initial and longitudinal in vivo non-invasive evaluation of macrophages infiltration and an assessment of therapy efficacy.

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