June 17th, 2013
•In Parkinson's disease and movement disorders in general, sensitive and reliable behavioral assays are essential for testing novel potential therapeutics. Here, we describe a manageable battery of sensorimotor tests for mice that are sensitive to varying degrees of injury to the nigrostriatal system and useful for preclinical studies.
Tags
Related Videos
Nest Building as an Indicator of Health and Welfare in Laboratory Mice
Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)
Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke
Behavioral Assessment of the Aging Mouse Vestibular System
Community-based Adapted Tango Dancing for Individuals with Parkinson's Disease and Older Adults
Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage
Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model
Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Low-Cost Gait Analysis for Behavioral Phenotyping of Mouse Models of Neuromuscular Disease
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved