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DOI :
10.3791/50720-v
September 18th, 2013
Chapters
0:05
Title
1:39
Phospho-protein Western Blot
3:02
Methylcellulose Assay
4:24
Evaluation of Phospho-protein Inhibition in vivo
5:39
Evaluation of Anti-leukemia Activity of TKIs in ALL Xenograft Models
8:13
Results: Biochemical and Functional Effects Mediated by TKIs
10:07
Conclusion
受容体チロシンキナーゼは、多くの癌において異所性に発現され、そして急性白血病における治療標的として同定されている。この原稿は、急性白血病の治療のためのチロシンキナーゼ阻害剤の前臨床評価のための効率的な戦略を記載している。
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