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Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression

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11:26 min

December 10th, 2014

December 10th, 2014

12,152 Views

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Title

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Equipment Set Up for Measurement of Oscillatory Lower Body Negative Pressure

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Measurement of Oscillatory Lower Body Negative Pressure

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Projection Pursuit Regression

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Results: Cerebral Autoregulation after Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression

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Conclusion

Cerebral perfusion is maintained across a range of pressures via cerebral autoregulation. However, characterizing autoregulation requires prominent pressure fluctuations at regulated frequencies. The described protocol will show how oscillatory lower body negative pressure can generate pressure fluctuations to provide data for projection pursuit regression for quantification of the autoregulatory curve.

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