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13.8K Views
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07:20 min
May 28th, 2014
DOI :
10.3791/51740-v
Chapters
0:05
Title
1:22
Synthesis of the N,N'-(alkane-1,n-diyl)diisonicotinamide
2:32
Purification of the Ligands
3:23
Synthesis and Purification of the Dinuclear Platinum Complexes
5:09
Results: Characterization of Bispyridine Ligands and Dinuclear Platinum Complexes
6:54
Conclusion
Summary
这个协议描述了使用异烟酸和二氨基烷烃的酰胺偶联反应,以形成适合于在多核铂配合物,其中结合的抗癌药物BBR3464和吡铂方面的合成中使用的桥接配体。
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