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Metodo chirurgico per Virally Mediated Gene consegna all'orecchio mouse interno attraverso la finestra rotonda a membrana

DOI :

10.3791/52187-v

March 16th, 2015

March 16th, 2015

14,663 Views

1Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco

The described post-auricular surgical approach allows rapid and direct delivery into the mouse cochlear scala tympani while minimizing blood loss and animal mortality. This method can be used for cochlear therapy using molecular, pharmacologic and viral delivery to postnatal mice through the round window membrane.

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Neuroscienze

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