Permanent Ligation av Venstre Anterior Synkende Coronary Artery i Mus: En modell av Post-hjerteinfarkt Remodelling og hjertesvikt

Heart failure is the leading cause of hospitalization and a major cause of mortality. A model of permanent ligation of the left anterior descending coronary artery in mice is applied to investigate ventricular remodelling and cardiac dysfunction post-myocardial infarction. The technique of invasive hemodynamic measurements in mice is presented.