Udvikling af inhibitorer af protein-protein interaktioner gennem REPLACE: Ansøgning til design og udvikling Ikke-ATP Konkurrencedygtige CDK hæmmere

1:57

Computational Identification of Potential Small Molecule Capping Groups

4:03

Synthesis of Potential N-capping Groups

6:25

Solid Phase Synthesis for the Generation of FLIPs

8:45

Results: Identification of More Drug-like Inhibitors of CDK2 through the Cyclin Groove

9:59

Conclusion