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A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice

14.5K Views

08:35 min

March 17th, 2015

March 17th, 2015

14,531 Views

0:05

Title

1:14

Preparing the Testing Plate and Enclosures

2:03

Performing the Cold Plantar Assay (CPA) at Fixed Temperatures

5:10

Testing the Mice During Cold Adaptation

5:54

Results: Measuring Analgesia and Hypersensitivity Using the Cold Planar Assay

8:00

Conclusion

The Cold Plantar Assay (CPA) measures cold responsiveness between 30 °C and 5 °C, and can also measure cold adaptation. This protocol describes how to use the CPA to measure cold hypersensitivity, analgesia, and adaptation in mice.

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