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Blessure chirurgicale au pancréas de souris par ligature du canal pancréatique tant que modèle de endocrines et exocrines Reprogrammation et prolifération

DOI :

10.3791/52765-v

August 7th, 2015

August 7th, 2015

15,823 Views

1Diabetes Research Center, Vrije Universiteit Brussel

This protocol describes an injury model involving the surgical ligation of the pancreatic duct in the adult mouse pancreas, resulting in severe injury that establishes an environment that allows beta cell neogenesis and proliferation. This model can be used as a tool to study mechanisms involved in beta cell formation.

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M decine

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