June 13th, 2016
•This manuscript describes an ex vivo model system comprised of organ-conditioned media derived from the lymph node, bone, lung, and brain of mice. This model system can be used to identify and study organ-derived soluble factors and their effects on the organ tropism and metastatic behavior of cancer cells.
Tags
Related Videos
An In Vitro System to Study Tumor Dormancy and the Switch to Metastatic Growth
Generation of Alginate Microspheres for Biomedical Applications
Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells
Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional (3D) Model
Tissue-simulating Phantoms for Assessing Potential Near-infrared Fluorescence Imaging Applications in Breast Cancer Surgery
Methods for Culturing Human Femur Tissue Explants to Study Breast Cancer Cell Colonization of the Metastatic Niche
Mammosphere Formation Assay from Human Breast Cancer Tissues and Cell Lines
An In Vitro Dormancy Model of Estrogen-sensitive Breast Cancer in the Bone Marrow: A Tool for Molecular Mechanism Studies and Hypothesis Generation
In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved