Results: Single Cell Resolution Protein Expression in Whole Mount Skin Preparations
6:55
Conclusion
Transcript
The overall goal of this procedure is to visualize cell proliferation and protein expression patterns at the single cell level in three dimensions and to accurately assess the anatomy and pathology of the skin. This method can help answer key ques
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Denne rapport beskriver en CUBIC protokol at afklare fuld tykkelse mus hud biopsier, og visualisere protein ekspressionsmønstre, prolifererende celler og sebocytter på enkelt celle opløsning i 3D. Denne metode giver nøjagtig vurdering af hudens anatomi og patologi, og af unormale epidermale fænotyper i genetisk modificerede mus linjer.