Sign In

JoVE Journal

Neuroscience

A subscription to JoVE is required to view this content.

live

Speed

×

MEDIA_ELEMENT_ERROR: Format error

Lateral Chronic Cranial Window Preparation Enables In Vivo Observation Following Distal Middle Cerebral Artery Occlusion in Mice

11.5K Views

08:41 min

December 29th, 2016

December 29th, 2016

11,498 Views

0:05

Title

0:43

Lateral Chronic Cranial Window Preparation

3:40

Intravital Microscopy

4:20

Distal Middle Cerebral Artery Occlusion (MCAo)

7:04

Results: Lateral Chronic Cranial Window with Distal MCAo

8:02

Conclusion

Transcript

The overall goal of this procedure is the preparation of a lateral cranial window combined with permanent middle cerebral artery occlusion. To facilitate longitudinal intravital microscopy in mice. This method can help to investigate and answer ke

Sign in or start your free trial to access this content

Surgical occlusion of a distal middle cerebral artery branch (MCAo) is a frequently used model in experimental stroke research. This manuscript describes the basic technique of permanent MCAo, combined with the insertion of a lateral cranial window, which offers the opportunity for longitudinal intravital microscopy in mice.

We use cookies to enhance your experience on our website.

By continuing to use our website or clicking “Continue”, you are agreeing to accept our cookies.

Learn More