Radiosynthesis of the 125I-labeled Azide Prosthetic Group
3:59
Radiolabeling of Dibenzocyclooctyne-group-modified Gold Nanoparticles via the Copper-free Click Reaction
5:53
Results: Validation of the Purified Radiolabeled Products
6:32
Conclusion
Transcript
The overall goal of this protocol is to provide an efficient and rapid synthetic method for radioactive iodine labeled gold nano particles using the strain promoted copper free click reaction. This method can help answer key questions in the radio
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A detailed procedure for the synthesis of a 125I-labeled azide and the radiolabeling of dibenzocyclooctyne (DBCO)-group-conjugated, 13-nm-sized gold nanoparticles using a copper-free click reaction is described.