We have developed a new murine model of de novo mammary cancer metastasis that closely mimics the course of human breast cancer, providing a preclinical platform for evaluating the biology, underlying metastatic progression of disease, and the eff
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Prækliniske modeller, der evaluerer adjuverende terapi rettet mod metastase i brystcancer, mangler. For at adressere dette udviklede vi en murin model af de novo pulmonal mammary adenocarcinom metastase, hvor terapier administreret i adjuvansindstillingen (postkirurgisk resektion af primære tumorer) kan evalueres for effektivitet ved påvirkning af tidligere podede lungemetastaser.