Administration of Test Substance and Preparation of FITC-Dextran
2:42
Preparation of the Left Jugular Vein and Injection of FITC-Dextran
3:51
Positioning the Right Ear for Intravital Fluorescence Microscopy
5:24
Intravital Fluorescence Microscopy and Thrombus Induction of the Right Ear
7:01
Venular Thrombus Formation after Single Cannabinoid Treatment and Cyclooxygenase Inhibition
8:03
Conclusion
Transcript
The overall goal of this experiment is to study the influence of potential vasoactive drugs on microvascular thrombus formation in vivo. This method can help answer key questions in thrombus formation such as identifying new antithrombotic substan
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Øret model af den hårløse SKH1-HR HR mus muliggør intravital fluorescensmikroskopi af mikrocirkulationen og fototoksiske trombe induktion uden forudgående kirurgisk forberedelse i det undersøgte mikrovaskulære leje. Derfor, i øret på den hårløse mus er en fremragende in vivo-model til at studere de komplekse vekselvirkninger under mikrovaskulær thrombedannelse, trombe evolution, og trombolyse.