cOVA-TH1 Cell Radiolabeling and Uptake and Efflux Analysis
6:44
Positron Emission Tomograph–Computed Tomography (PET/CT) In Vivo Imaging
8:26
Results: Representative cOVA-TH1 Cell Tracking In Vitro and In Vivo
10:32
Conclusion
Transcript
The overall goal of this procedure is to stably label murine lymphocytes with a copper-modified radioactive monoclonal antibody to track lymphocyte temporal distribution and homing patterns in vivo by PET/CT in mouse models of inflammation or canc
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Efter fremstillingen af en 64 Cu-modificeret monoklonalt antistofbinding til en transgen murin T-cellereceptor, T-celler radiomærkes in vivo, analyseret for levedygtighed, funktionalitet, stabilitet mærkning og apoptose og adoptivt overført i mus med en luftvej forsinket hypersensitivitet reaktionen til ikke-invasiv billeddannelse ved positronemissionstomografi / computertomografi (PET / CT).