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DOI :
10.3791/55384-v
May 10th, 2017
Chapters
0:05
Title
11:22
Conclusion
9:53
Results: Achieving Physiological Levels of the Human TSLP Cytokine in PDX Mice
1:22
Culture and Expansion of Cytokine Transduced Stromal Cells
3:05
Phospho-flow Cytometry Analysis of Stroma-produced Cytokine Activity
5:09
Injection of Cytokine-transduced Stroma into Mice
6:22
Serial Blood Collection and Plasma Monitoring of Exogenous Human Cytokine in Mice
8:33
Human Hematopoietic Cell Transplantation
ここで、サイトカイン形質導入間質細胞株の毎週腹腔内注射による患者由来異種移植(PDX)マウスにおける外因性サイトカインの産生方法を記載する。この方法は、PDXの有用性を広げ、多数のPDXモデルにおける一過性または持続性外因性サイトカイン送達の選択肢を提供する。
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