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JoVE Journal

Medicine

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In Vivo Evaluation of the Mechanical and Viscoelastic Properties of the Rat Tongue

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06:59 min

July 6th, 2017

July 6th, 2017

8,587 Views

0:05

Title

0:59

Hypoglossal Nerve Identification

2:19

Tracheal Intubing and Tongue Suturing

3:36

Optimal Length (L0), Maximal Isometric Force, and Viscoelastic Properties Determination (Lissajous Curves)

5:30

Results: Representative Force and Displacement Analyses

6:26

Conclusion

Transcript

The overall goal of this procedure is to assess the strength and viscoelastic properties of the tongue in anesthetized rats. This method can help answer key questions in the field of sleep disordered breathing, about obstructive sleep apnea. The m

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We describe a surgical procedure in an anesthetized rat model for determining the muscle tone and viscoelastic properties of the tongue. The procedure involves specific stimulation of the hypoglossal nerves and application of passive Lissajous force/deformation curves to the muscle.

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