Results: Repetitive Injection of PTZ Induces an Increase in Seizure Severity
6:26
Conclusion
Transcript
This method can help the deep analysis of epilepsy. Seizure will induce histological changes in the brain which may be involved in the neuropsychiatric developmental disorders. The main advantage with this technique is that self-conversive dose of
Sign in or start your free trial to access this content
This protocol describes a method of chemical kindling with pentylenetetrazole and provides a mouse model of epilepsy. This protocol can also be used to investigate vulnerability to seizure induction and pathogenesis after epileptic seizures in mice.