Transfection of HEK293 Cells with NR1-GFP Expression Plasmid
2:38
Cell-based Immunofluorescence Assay
4:41
Results: Anti-NMDA Receptor Autoantibodies Detected in the Blood of Patients with Autoimmune Encephalitis
6:12
Conclusion
Transcript
The overall goal of this assay is to detect autoantibodies against the NMDA receptor in the blood of patients with suspected autoimmune encephalitis. The measure help answer the key questions in differential diagnosis of patients with acute neuro-
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Vi uttrykte ectopically NR1 delenhet i NMDA reseptor merket med grønne fluorescerende protein i menneskelige embryonale celler (HEK293) som antigen å oppdage autoantistoffer mot NMDA reseptor i blodet av pasienter mistenkt med autoimmune encefalitt. Denne enkle metoden kan være passende for screening formål i klinisk innstillinger.