Results: Toxicological Assessment of Changes in the Intracellular EGSH as Measured by roGFP2
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Conclusion
Transcript
The overall goal of this methodology is to establish the use of genetically-encoded redox sensors for the specific assessment of toxicant-induced perturbations in redox homeostasis. By overcoming the significant limitations of conventional approac
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Dette manuskript beskriver brugen af genetisk kodet fluorogenic journalister i et program af live-celle imaging til gennemgang af xenobiotiske-induceret oxidativt stress. Denne eksperimentelle tilgang tilbyder uovertruffen spatiotemporelle opløsning, følsomhed og specificitet samtidig undgå mange af manglerne ved konventionelle metoder, der anvendes til påvisning af toksikologiske oxidativt stress.