Seeding the Cells on Ultra-low Adhesion Cell Culture Plates and Exposing Spheroids to Multimodal Standard or Experimental Tumor Therapy
2:52
Assessment of Spheroid Size and Extent of Cellular Proliferation for Assay Read-out
4:08
Results: Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
5:12
Conclusion
Transcript
The overall goal of this in vitro method is to generate the three dimensional cell culture spheroids that enable the testing of current standard or experimental therapy regimens for head and neck squamous cell carcinoma. This method helps us to un
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Descrevemos a evolução de um modelo tridimensional, esferoide-baseado em vitro que permite-nos testar o padrão atual de regimes de terapia experimental para cabeça e pescoço carcinoma de células escamosas na linha de celular, com o objetivo de avaliar a terapia susceptibilidade e resistência em células primárias de espécimes humanos no futuro.