Name: photoselective vaporesection of the prostate via an end-firing lithium triborate crystal laser
Uploaded: 2018-05-09T14:00:00
Description: Watch this Scientific Journal Video about Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser at JoVE.com

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Tutti i metodi descritti qui sono stati approvati dal comitato etico dell'ospedale di Pechino. Indicazioni per la chirurgia sono secondo gli orientamenti dell'associazione europea di urologia per nonneurogenic maschio LUTS. Le controindicazioni includono sospetta disfunzione della prostata cancro o detrusore.
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<ol>
	<li>Capit&#225;n, C., Bl&#225;zquez, C., Martin, M. D., Hern&#225;ndez, V., de la Pe&#241;a, E., Llorente, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=GreenLight+HPS+120W+laser+vaporization+versus+transurethral+resection+of+the+prostate+for+the+treatment+of+lower+urinary+tract+symptoms+due+to+benign+prostatic+hyperplasia:+A+randomized+clinical+trial+with+2-year+follow-up.">GreenLight HPS 120W laser vaporization versus transurethral resection of the prostate for the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia: A randomized clinical trial with 2-year follow-up.</a> Eur Urol. 60 (4), 734-739 (2011).</li><li>Cornu, J. N., Ahyai, S., Bachmann, A., de la Rosette, J., Gilling, P., Gratzke, C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+systematic+review+and+meta-analysis+of+functional+outcomes+and+complications+following+transurethral+procedures+for+lower+urinary+tract+symptoms+resulting+from+benign+prostatic+obstruction:+An+update.">A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: An update.</a> Eur Urol. 67 (6), (2014).</li><li>Kang, H. W., Jebens, D., Malek, R. S., Mitchell, G., Koullick, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Laser+vaporization+of+bovine+prostate:+A+quantitative+comparison+of+potassium-titanyl-phosphate+and+lithium+triborate+lasers.">Laser vaporization of bovine prostate: A quantitative comparison of potassium-titanyl-phosphate and lithium triborate lasers.</a> J Urol. 180 (6), 2675-2680 (2008).</li><li>Herrmann, T. R., Liatsikos, E. N., Nagele, U., Traxer, O., Merseburger, A. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=EAU+Guidelines+Panel+on+Lasers,+Technologies.+EAU+guidelines+on+laser+technologies.">EAU Guidelines Panel on Lasers, Technologies. EAU guidelines on laser technologies.</a> Eur Urol. 61 (4), 783-795 (2012).</li><li>Braeckman, J., Denis, L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Management+of+BPH+then+2000+and+now+2016+-+From+BPH+to+BPO.">Management of BPH then 2000 and now 2016 - From BPH to BPO.</a> Asian J Urol. 4 (3), 138-147 (2017).</li><li>Bachmann, A., Tubaro, A., Barber, N., d'Ancona, F., Muir, G., Witzsch, U., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+European+multicenter+randomized+noninferiority+trial+comparing+180+W+GreenLight+XPS+laser+vaporization+and+transurethral+resection+of+the+prostate+for+the+treatment+of+benign+prostatic+obstruction:+12-month+results+of+the+GOLIATH+study.">A European multicenter randomized noninferiority trial comparing 180 W GreenLight XPS laser vaporization and transurethral resection of the prostate for the treatment of benign prostatic obstruction: 12-month results of the GOLIATH study.</a> J Urol. 193 (2), 570-578 (2015).</li><li>Peyronnet, B., Pradere, B., Brichart, N., Bodin, T., Bertrand, P., Members of French Group of GreenLight Users, ., Bruy&#232;re, F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Complications+associated+with+photoselective+vaporization+of+the+prostate:+Categorization+by+a+panel+of+GreenLight+users+according+to+Clavien+score+and+report+of+a+single-center+experience.">Complications associated with photoselective vaporization of the prostate: Categorization by a panel of GreenLight users according to Clavien score and report of a single-center experience.</a> Urology. 84 (3), 657-664 (2014).</li><li>Cho, S. Y., Park, S., Jeong, M. Y., Ro, Y. K., Son, H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=120W+GreenLight+high+performance+system+laser+for+benign+prostate+hyperplasia:+68+patients+with+3-year+follow-up+and+analysis+of+predictors+of+response.">120W GreenLight high performance system laser for benign prostate hyperplasia: 68 patients with 3-year follow-up and analysis of predictors of response.</a> Urology. 80 (2), 396-401 (2012).</li><li>Elmansy, H. M., Elzayat, E., Elhilali, M. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Holmium+laser+ablation+versus+photoselective+vaporization+of+prostate+less+than+60+cc:+Long-term+results+of+a+randomized+trial.">Holmium laser ablation versus photoselective vaporization of prostate less than 60 cc: Long-term results of a randomized trial.</a> J Urol. 184 (5), 2023-2028 (2010).</li><li>Hong, K., Liu, Y. Q., Lu, J., Xiao, C. L., Huang, Y., Ma, L. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Efficacy+and+safety+of+120W+thulium:+Yttrium-aluminum-garnet+vapoenucleation+of+prostates+compared+with+holmium+laser+enucleation+of+prostates+for+benign+prostatic+hyperplasia.">Efficacy and safety of 120W thulium: Yttrium-aluminum-garnet vapoenucleation of prostates compared with holmium laser enucleation of prostates for benign prostatic hyperplasia.</a> Chin Med J (Engl). 128 (7), 884-889 (2015).</li><li>Hermanns, T., Sulser, T., Fatzer, M., Baumgartner, M. K., Rey, J. M., Sigrist, M. W., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Laser+fiber+deterioration+and+loss+of+power+output+during+photo-selective+80-W+potassiumtitanyl-phosphate+laser+vaporization+of+the+prostate.">Laser fiber deterioration and loss of power output during photo-selective 80-W potassiumtitanyl-phosphate laser vaporization of the prostate.</a> Eur Urol. 55 (3), 679-686 (2009).</li><li>Hermanns, T., Strebel, D. D., Hefermehl, L. J., Gross, O., Mortezavi, A., M&#252;ller, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Lithium+triborate+laser+vaporization+of+the+prostate+using+the+120+W,+high+performance+system+laser:+High+performance+all+the+way?.">Lithium triborate laser vaporization of the prostate using the 120 W, high performance system laser: High performance all the way?.</a> J Urol. 185 (6), 2241-2247 (2011).</li><li>Schwartz, J., Renard, J., Wolf, J. P., Moret, M., Iselin, C. E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=High-power+potassium-titanyl-phosphate+laser+fibres+for+endovaporization+of+benign+prostatic+hyperplasia:+How+much+do+they+deteriorate+during+the+procedure?.">High-power potassium-titanyl-phosphate laser fibres for endovaporization of benign prostatic hyperplasia: How much do they deteriorate during the procedure?.</a> BJU Int. 107 (12), 1938-1942 (2011).</li><li>Son, H., Ro, Y. K., Min, S. H., Choo, M. S., Kim, J. K., Lee, C. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Modified+vaporization-resection+for+photoselective+vaporization+of+the+prostate+using+a+GreenLight+high+-performance+system+120-W+Laser:+the+Seoul+technique.">Modified vaporization-resection for photoselective vaporization of the prostate using a GreenLight high -performance system 120-W Laser: the Seoul technique.</a> Urology. 77 (2), 427-432 (2011).</li><li>Mandal, S., Sankhwar, S. N., Kathpalia, R., Singh, M. K., Kumar, M., Goel, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Grading+complications+after+transurethral+resection+of+prostate+using+modified+Clavien+classification+system+and+predicting+complications+using+the+Charlson+comorbidity+index.">Grading complications after transurethral resection of prostate using modified Clavien classification system and predicting complications using the Charlson comorbidity index.</a> Int Urol Nephrol. 45 (2), 347-354 (2013).</li><li>Gong, Y. G., Liu, R. M., Gao, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Photoselective+vaporesection+of+the+prostate+with+a+front-firing+lithium+triborate+laser:+Surgical+technique+and+experience+after+215+procedures.">Photoselective vaporesection of the prostate with a front-firing lithium triborate laser: Surgical technique and experience after 215 procedures.</a> Eur Urol. 67 (6), 1142-1159 (2015).</li></ol>

Qui, condividiamo le nostre esperienze con PVRP. In primo luogo, PVRP abilitato migliore esposizione della capsula della prostata con adeguata delimitazione e ridotto il rischio di perforazione capsula. In secondo luogo, la rimozione di tessuto dovrebbe essere effettuata lungo la capsula chirurgica, soprattutto con la scanalatura a 12, che facilita la resezione del tessuto intorno al tetto dell'uretra prostatica e fornisce un tasso di rimozione del tessuto soddisfacente. In terzo luogo, è essenziale per rimuovere il lob...

Sebbene la resezione transuretrale della prostata (TURP) è ancora accettata come il gold standard nel trattamento chirurgico di iperplasia prostatica benigna (BPH), interventi chirurgici laser gradualmente sono diventati più popolari a causa della tolleranza del paziente migliore, meno intraoperatoria perdita di sangue, un'efficacia soddisfacente e più breve recupero postoperatorio1,2,3. Attualmente, i laser più comunemente utilizzati per il trattamento di BPH in tutto il mondo sono generati da litio potassio titanil fosfato o litio triborate (LBO) cristalli4,5. Tradizionalmente, questi sono classificati come sidefiring laser rispetto ad altri tipi di laser, come il laser a olmio e Tulio laser.
Fotoselettive vaporizzazione della chirurgia della prostata (PVP) potrebbe diminuire considerevolmente sindrome TURP dovuto irrigazione salina6,7e rispetto ad altri tipi di laser, l'efficacia affidabile della sindrome più bassa dell'apparato urinario (LUTS) da PVP è stata verificata da una serie di studi8,9,10. Tuttavia, PVP associati con emissione laser lato-infornamento ha anche alcuni svantaggi, tra cui una perdita di energia di quasi il 20% e una durata breve del laser della fibra11,12,13. Inoltre, PVP aumenta la possibilità di mancata diagnosi di carcinoma della prostata a causa di vaporizzazione completa del tessuto.
L'introduzione di Photoselective Vaporesection della prostata (PVRP) con una fibra fine-infornamento superato con successo la maggior parte degli svantaggi di PVP di cui sopra. In primo luogo, la punta è in grado di trasmissione laser ai tessuti con quasi nessuna perdita di energia intraoperatively. In secondo luogo, quando i detriti fibra raccoglie sulla punta, è semplice per mantenere la potenza di uscita ideale semplicemente rimuovendo le parti interessate. Infine, la resezione del laser consente la raccolta di campioni per esame patologico postoperatorio. Quindi, utilizzando questo protocollo nel trattamento di BPH potrebbe che permettono di migliorare il tasso di rimozione del tessuto, salvare il tempo operatorio e migliorare la sicurezza intraoperatoria.

<table border="0" cellpadding="0" cellspacing="0" width="1026">
	<tbody>
		<tr height="124">
			<td height="124" style="height:124px;width:279px;">FLARE surgical Laser Fiber</td>
			<td style="width:152px;">REALTON</td>
			<td style="width:119px;"></td>
			<td style="width:477px;">The FLARE Surgical laser Fiber is a 600 micron fiber with an straight tip that transmits the laser energy directly. this product is packaged sterile for disposable use and should not be re-sterilized or reused. Dispose of properly after use.</td>
		</tr>
		<tr height="213">
			<td height="213" style="height:213px;width:279px;">AURORA Surgical Green Laser System</td>
			<td style="width:152px;">REALTON</td>
			<td style="width:119px;">pvp-160-021</td>
			<td style="width:477px;">The AURORA Surgical green laser system is a diode-pumped, frequency-doubled Nd:YAG solid state laser. The AURORA Surgical green laser system features a &#8220;Plug and Play&#8221; capability that self-adjusts to the facility&#8217;s individual voltage requirements, eliminating the need for electrical modifications. The laser system also includes an air-cooled internal mechanism, ensuring safe operating temperatures with no external water connections. Laser energy emission and system status selection is activated through a surgeon-controlled, color-coded footswitch or system touch screen feature located in the laser console.</td>
		</tr>
	</tbody>
</table>

photoselective vaporesection of the prostate via an end-firing lithium triborate crystal laser

L'avvenimento dei sintomi più bassi dell'apparato urinario (LUTS) causato da iperplasia prostatica benigna (BPH) è un problema comune con un'alta incidenza nella popolazione maschio di invecchiamento. Anche se non si tratta di una malattia pericolosa, BPH provoca problemi che incidono gravemente la qualità della vita. Qui, presentiamo una nuova tecnica chiamata fotoselettive vaporesection della prostata (PVRP) nel trattamento di BPH, che può essere visto come una variante di fotoselettive vaporizzazione della prostata (PVP). Questa procedura presenta diversi vantaggi rispetto alla tecnica PVP tra cui minore perdita di energia laser, meno complicanze intraoperatorie, nonché più tasso di resezione del tessuto.

Un totale di 35 pazienti che hanno subito il PVRP sono stati inclusi in uno dei nostri studi. L'età paziente media era di 72,1 ± 7,1 anni (range 53-85 anni).
Dati di Perioperative sono elencati nella tabella 1. Il tempo di emissione del laser media hanno rappresentato quasi il 50% del tempo operatorio medio. La perdita di sangue nella maggior parte dei pazienti era < 200 mL. Tuttavia, la media deviato a causa ...

Watch this Scientific Journal Video about Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser at JoVE.com

Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser

Qui presentiamo un protocollo per eseguire Photoselective Vaporesection della prostata (PVRP) per trattamento di iperplasia prostatica benigna (BPH).

Fotoselettive Vaporesection della prostata tramite un Laser di cristallo Triborate litio fine-infornamento

The occurrence of lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) is a common problem with a high incidence in the aging ...

The overall goal of this procedure is to treat benign prostatic hyperplasia in a minimally invasive manner. This method can be used to effectively treat benign prostatic hyperplasia while preserving tissue for postoperative pathological examination. Other advantages of this technique include a low rate of laser energy loss and fewer intraoperative complications.The implication of this technique extend toward the therapy of benign prostatic hyperplasia as it's safer and quicker than traditional method. Generally, people new to this method will struggle until they have mastered the transurethal resection of the prostate. Visual demonstrations of this method is critical as several key steps are difficult to learn by text instruction alone.Thirty minutes before beginning the procedure, administer a preoperative antibiotic. To begin the procedure, have the patient lay down on the operating table in the dorsal lithotomy position and cover the patient with a sterile drape. Next, distend the bladder with 300 to 400 milliliters of saline and use a 26 F laser resectoscope to examine the whole bladder cavity and prostatic urethra.Use a lithium triborate crystal laser to mark two lines starting at five and seven o'clock on the bladder neck continuing along the boundaries between the median and lateral lobes and merging adjacent to the proximal margin of the verumontanum. Set the laser power to 100 watts and use laser vaporization along the lines to vaporize the prostate until white cyclic fibers are observed. Adjust the laser power to 120 watts and use the laser fiber to mark several more lines on the surface of the wedge-shaped middle lobe.Using vaporization, divide the middle lobe into several chunks along the lines splitting each chunk from the middle lobe. Then remove the whole middle lobe. For vaporesection of the lateral lobes, rotate the cytoscope 180 degrees to vaporize the tissue at 12 o'clock from the apex of the prostate to the bladder neck.When the vaporesection is complete, locate the lower margins of both lateral lobes and set another two grooves originating from the bladder neck at three and nine o'clock to the proximal end of the verumontanum. To remove the tissue of the lateral gland, use the laser fiber to mark several lines on the surface of the left lobe. Vaporize the left lobe into several chunks along the lines and split each chunk from the lobe.Then remove the whole left lobe and remove the remnant gland tissue along the existing boundary of the capsule. To enhance the integrity of the cavity, set the laser to 80 watts and vaporize any protruding tissue around the apex of the gland. Next, use a glass syringe that matches the interface of the resectoscope to remove any final tissue chunks by water flow.Use the resectoscope to confirm a lack of residual tissue in the bladder and prostatic fossa and the integrity of urethral orifices. Use the laser fiber to stop the bleeding around the surgical site. After removing the resectoscope, lubricate the urethra with iodine gel.Then insert a 22 French Foley catheter from the urethral orifice to the bladder cavity and gently fill the balloon with 30 milliliters of water. In this representative study of 35 patients who underwent photoselective vaporesection of the prostate, the mean laser emission time accounted for nearly 50%of the mean operative time and the blood loss in most patients was less than 200 milliliters. Almost 90%of the patients had the catheter removed within six days postoperatively.All patients returned to the hospital for followup examinations at one and three months postprocedure. According to the modified Clavien-Dindo classification system, only two cases of perioperative complications were grade 3b and only one case required treatment. Three patients experienced high febrility due to an acute Urinary Tract Infection or UTI on postoperative days five to six and all three patients received antibiotics and recovered rapidly.Five patients complained of urgency and frequency, but in three patients, the urine culture revealed no abnormalities allowing UTI to be excluded. The other two patients were diagnosed with UTI and recovered after effective antibiotic courses. Only a single patient experienced persistent urinary incontinence in the early postoperative period without the evidence of the UTI that was fully resolved after several weeks of pelvic floor muscles training.Another patient had difficulty voiding and was diagnosed with bladder neck contracture via cystoscopy that was resolved after a bladder neck incision under general anesthesia on day 40 after the original procedure. Once mastered, this procedure can be completed in two hours if it is performed properly. While attempting this procedure, it is important to take care to avoid the intraoperative complications.After watching this video, you should have a good understanding of how to photoselectively vaporesect prostate for the alleviation of the symptoms associated with benign prostatic hyperplasia.

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