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DOI :
10.3791/57351-v
May 25th, 2018
Chapters
0:05
Title
0:56
Device Preparation
2:31
Canalostomy in Adult Mice
5:58
Canalostomy in Neonatal Mice
6:48
Results: Drug Delivery by Canalostomy Resulted in Widespread Distribution of the Reagent Throughout the Cochlea and Vestibular End-organs
8:13
Conclusion
在这里, 我们描述了 canalostomy 程序, 允许当地药物传递到成年和新生小鼠的内耳通过半圆形运河, 对听力和前庭功能的最小损害。该方法可用于将病毒载体、药物和小分子接种到小鼠内耳内。
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