Differentiation of hPSCs into Cryopreservable First Heart Field-like Cardiac Progenitors (FHF-L CPs)
4:38
FHF-L CP Differentiation into Ventricular-like Cardiomyocytes
6:28
Use of Activin A and Lentivirus-mediated Id1 Overexpression to Generate Ventricular-like Cardiomyocytes
8:12
Conclusion
Transcript
The main advantage of this simple technique is to generate cardiac progenitors and cardiomyocytes of defined heart field origin and subtypes. In turn, resulting cells can be used for a wide range of research application, including basic developmen
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Her beskriver vi en skalerbar metode, ved hjælp af en simpel kombination af Activin A og lentivirus-medieret Id1-overekspression, til at generere første hjertet felt-lignende hjerte ophav og ventrikel-lignende cardiomyocytes fra humane pluripotente stamceller.