Results: Representative Mature RPE Cell Status Validation
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Conclusion
Transcript
This method can help answer key questions in the ion-channel related retinal diseases field about the molecular mechanisms of BEST1 mutations and pathology of bestrophinopathies. The main advantage of this technique is that it circumvents the diff
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Her presenterer vi en protokoll for å skille netthinnens pigment epitel (RPE) celler fra menneskelige pluripotent stamceller bærer pasient-avledede mutasjoner. De muterte cellelinjer kan brukes for funksjonell analyser inkludert immunoblotting, immunofluorescence og patch klemme. Denne sykdommen-i-en-fat omgår vanskelighetene med å skaffe innfødt menneskelige RPE celler.