Preparation of the Calibrators, Quality Control Samples, and Internal Standards Mix
2:29
Buffer Preparation for Chromatography
3:47
Sample Cleanup and HPLC-MS/MS Analysis
6:28
Quality Assessment and Quantification
8:14
Results: Data Analysis and Quantification of Piperacillin
9:44
Conclusion
Transcript
Therapeutic drug monitoring of antibiotics is increasingly recognized as an important element for the implementation of national and local antibiotic stewardship programs. To meet this increasing demand of antibiotic therapeutic drug monitoring in
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Her præsenterer vi en tandem massespektrometri-baseret protokol til kvantificering af ofte anvendte antibiotika i intensivafdelinger, nemlig cefepime, meropenem, ciprofloxacin, moxifloxacin, linezolid og piperacillin.