Lipophilicity Determination, Tumor Model Preparation, In Vivo Quantification, and Ex Vivo Biodistribution
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Results: Representative 68Ga-RGD-peptide Purification, Radiochemical Purity, and In Vivo Imaging and Ex Vivo Biodistribution Analyses
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Conclusion
Transcript
This method can help answer key questions in the preparation of the Gallium 68 labeled RGD-Peptide and the method for the biological evaluation of its analogs. The main advantage of this technique is that it is a simple systemic protocol for the d
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The αvβ3 integrin is a type of adhesion protein that is highly expressed on activated endothelial cells undergoing angiogenesis. Thus, evaluating the integrity of the integrin is of great interest in oncology. Here, we introduce a method to prepare 68Ga-labeled radiopeptides and a method to assess its biological effectiveness.