This method aims to model overeating and subsequent obesity by providing access to a wide variety of palatable foods high in sugar and saturated fat. The variety and palatability of the diet ensures that overeating is reliably promoted, leading to
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This protocol describes the use of a highly palatable, western-style cafeteria diet to model overeating and obesity in rodents. Here, we provide a detailed outline of food selection, preparation and measurement, and explain methodological factors that assist in generating a robust and reproducible phenotype.