The overall goal of the following experiment in genetically trackable design Caenorhabditis elegans is to identify tissue-specific chaperone interactions. The main advantage of this technique is that it combines easy to use assays such as fitting
Sign in or start your free trial to access this content
For at studere chaperone-chaperone og chaperone-substrat interaktioner, udfører vi syntetiske interaktion skærme i Caenorhabditis elegans ved hjælp af RNA interferens i kombination med milde mutationer eller over-udtryk for chaperoner og overvåge vævsspecifikke protein dysfunktion på organismeniveau.