Results: Quantification of Antimicrobial Effects on In Vitro Biofilm Architecture
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Conclusion
Transcript
The significance of this protocol is that it offers a simple and reproducible framework for quantifying in vitro biofilm structures under varying antimicrobial conditions. The main advantage of this technique is that it helps eliminate subjective
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Antimikrobielt inducerede ændringer i Pseudomonas aeruginosa biofilmarkitektur adskiller sig blandt kliniske isolater dyrket fra patienter med cystisk fibrose og kronisk lungeinfektion. Efter konfokalmikroskopi kan COMSTAT-software bruges til at kvantificere variationer i biofilmarkitektur (f.eks. overfladeareal, tykkelse, biomasse) for individuelle isolater for at vurdere effektiviteten af anti-infektiøse midler.