September 15th, 2021
•The genome is organized in the nuclear space into different structures that can be revealed through chromosome conformation capture technologies. The in-nucleus Hi-C method provides a genome-wide collection of chromatin interactions in Drosophila cell lines, which generates contact maps that can be explored at megabase resolution at restriction fragment level.
Tags
Related Videos
In Situ Labeling of Mitochondrial DNA Replication in Drosophila Adult Ovaries by EdU Staining
Quantifying Abdominal Pigmentation in Drosophila melanogaster
Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
Purification of Low-abundant Cells in the Drosophila Visual System
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
In Vivo Forward Genetic Screen to Identify Novel Neuroprotective Genes in Drosophila melanogaster
Use of Drosophila S2 Cells for Live Imaging of Cell Division
Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
A FACS-based Protocol to Isolate RNA from the Secondary Cells of Drosophila Male Accessory Glands
Detection of Post-Replicative Gaps Accumulation and Repair in Human Cells Using the DNA Fiber Assay
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved