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JoVE Journal

Neuroscience

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Shuttle Box Assay as an Associative Learning Tool for Cognitive Assessment in Learning and Memory Studies using Adult Zebrafish

4.2K Views

08:35 min

July 12th, 2021

July 12th, 2021

4,245 Views

0:05

Introduction

0:32

Shuttle Box Learning Paradigm

2:47

Memory Paradigm

6:08

Results: Shuttle Box Assay as anAssociative Learning Tool for Cognitive Assessment in Learning and Memory Studies using Adult Zebrafish

7:58

Conclusion

Transcript

The Shuttle Box Assay reproducibly tracks the progression and recovery of cognitive impairment following a blunt force trauma or any other type of brain injury in zebrafish. The Shuttle Box Assay allows for relatively simple, rapid and robust meas

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Learning and memory are potent metrics in studying either developmental, disease-dependent, or environmentally induced cognitive impairments. Most cognitive assessments require specialized equipment and extensive time commitments. However, the shuttle box assay is an associative learning tool that utilizes a conventional gel box for rapid and reliable assessment of adult zebrafish cognition.

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