Name: c-arm-free simultaneous olif51 and percutaneous pedicle screw fixation in a single lateral position
Uploaded: 2022-09-16T13:00:00
Description: Watch this Scientific Journal Video about C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position at JoVE.com

这项研究得到了冈山脊柱小组的支持。

本研究获得冈山玫瑰医院伦理委员会（No. 201-3）的批准。
1. 患者检查
<ol><li>历史采集<ol>
<li>通过采集病史来评估疑似椎间盘突出或狭窄的患者。通常，患者有前驱腰痛病史。患者可能将其症状与创伤发作相关联。</li>
		<li>要求患者描述放射性腿部疼痛、其位置以及加重和缓解活动。</li>
	</ol>
</li>
	<li>体检<ol>
<li>为了确定受累神经的水平，寻找腿部运动无力或感?...

<ol>
	<li>Tawfik, S., Phan, K., Mobbs, R. J., Rao, P. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+incidence+of+pars+interarticularis+defects+in+athletes.">The incidence of pars interarticularis defects in athletes.</a> Global Spine Journal. 10 (1), 89-101 (2020).</li><li>Sonne-Holm, S., Jacobsen, S., Rovsing, H. C., Monrad, H., Gebuhr, P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Lumbar+spondylolysis:+A+life+long+dynamic+condition?+A+cross+sectional+survey+of+4.151+adults.">Lumbar spondylolysis: A life long dynamic condition? A cross sectional survey of 4.151 adults.</a> European Spine Journal. 16 (6), 821-828 (2007).</li><li>McAfee, P. C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+indications+for+interbody+fusion+cages+in+the+treatment+of+spondylolisthesis:+Analysis+of+120+cases.">The indications for interbody fusion cages in the treatment of spondylolisthesis: Analysis of 120 cases.</a> Spine. 30 (6), 60-65 (2005).</li><li>Parajon, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Minimally+invasive+transforaminal+lumbar+interbody+fusion:+Meta-analysis+of+the+fusion+rates.+What+is+the+optimal+graft+material.">Minimally invasive transforaminal lumbar interbody fusion: Meta-analysis of the fusion rates. What is the optimal graft material.</a> Neurosurgery. 81 (6), 958-971 (2017).</li><li>Lowe, T. G., Tahernia, A. D., O'Brien, M. F., Smith, D. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Unilateral+transforaminal+posterior+lumbar+interbody+fusion+(TLIF):+Indications,+technique,+and+2-year+results.">Unilateral transforaminal posterior lumbar interbody fusion (TLIF): Indications, technique, and 2-year results.</a> Journal of Spinal Disorders and Techniques. 15 (1), 31-38 (2002).</li><li>Mayer, H. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+new+microsurgical+technique+for+minimally+invasive+anterior+lumbar+interbody+fusion.">A new microsurgical technique for minimally invasive anterior lumbar interbody fusion.</a> Spine. 22 (6), 691-699 (1997).</li><li>Hodgson, A. R., Stock, F. E., Fang, H. S. Y., Ong, G. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Anterior+spinal+fusion+the+operative+approach+and+pathological+findings+in+412+patients+with+Pott's+disease+of+the+spine.">Anterior spinal fusion the operative approach and pathological findings in 412 patients with Pott's disease of the spine.</a> The British Journal of Surgery. 48, 172-178 (1960).</li><li>Woods, K., Billy, J. B., Hynes, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Technical+description+of+oblique+lateral+interbody+fusion+at+L1-L5+(OLIF25)+and+at+L5-S1+(OLIF51)+and+evaluation+of+complication+and+fusion+rates.">Technical description of oblique lateral interbody fusion at L1-L5 (OLIF25) and at L5-S1 (OLIF51) and evaluation of complication and fusion rates.</a> The Spine Journal. 17 (4), 545-553 (2017).</li><li>Tan, Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Comparison+of+simultaneous+single-position+oblique+lumbar+interbody+fusion+and+percutaneous+pedicle+screw+fixation+with+posterior+lumbar+interbody+fusion+using+O-arm+navigated+technique+for+lumbar+degenerative+diseases.">Comparison of simultaneous single-position oblique lumbar interbody fusion and percutaneous pedicle screw fixation with posterior lumbar interbody fusion using O-arm navigated technique for lumbar degenerative diseases.</a> Journal of Clinical Medicine. 10 (21), 4938 (2021).</li><li>Phillips, F. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Adult+degenerative+scoliosis+treated+with+XLIF:+Clinical+and+radiographical+results+of+a+prospective+multicenter+study+with+24-month+follow-up.">Adult degenerative scoliosis treated with XLIF: Clinical and radiographical results of a prospective multicenter study with 24-month follow-up.</a> Spine. 38 (21), 1853-1861 (2013).</li><li>Davis, T. T., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Retroperitoneal+oblique+corridor+to+the+L2-S1+intervertebral+discs+in+the+lateral+position:+An+anatomic+study.">Retroperitoneal oblique corridor to the L2-S1 intervertebral discs in the lateral position: An anatomic study.</a> Journal of Neurosurgery: Spine. 21 (5), 78 (2014).</li><li>Houten, J. K., Alexandre, L. C., Nasser, R., Wollowick, A. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Nerve+injury+during+the+transpsoas+approach+for+lumbar+fusion.">Nerve injury during the transpsoas approach for lumbar fusion.</a> Journal of Neurosurgery: Spine. 15 (3), 280-284 (2011).</li><li>Tanaka, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=C-arm+free+simultaneous+OLIF51+and+percutaneous+pedicle+screw+fixation+in+a+single+lateral+position:+A+technical+note.">C-arm free simultaneous OLIF51 and percutaneous pedicle screw fixation in a single lateral position: A technical note.</a> Interdisciplinary Neurosurgery. 27, 101428 (2022).</li><li>Hadelsberg, U. P., Harel, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Hazards+of+ionizing+radiation+and+its+impact+on+spine+surgery.">Hazards of ionizing radiation and its impact on spine surgery.</a> World Neurosurgery. 92, 353-359 (2016).</li><li>Kim, T. T., Drazin, D., Shweikeh, F., Pashman, R., Johnson, J. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Clinical+and+radiographic+outcomes+of+minimally+invasive+percutaneous+pedicle+screw+placement+with+intraoperative+CT+(O-arm)+image+guidance+navigation.">Clinical and radiographic outcomes of minimally invasive percutaneous pedicle screw placement with intraoperative CT (O-arm) image guidance navigation.</a> Neurosurgical Focus. 36 (3), 1 (2014).</li><li>Kakarla, U. K., Little, A. S., Chang, S. W., Sonntag, V. K., Theodore, N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Placement+of+percutaneous+thoracic+pedicle+screws+using+neuronavigation.">Placement of percutaneous thoracic pedicle screws using neuronavigation.</a> World Neurosurgery. 74 (6), 606-610 (2010).</li><li>Nagamatsu, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Assessment+of+3D+lumbosacral+vascular+anatomy+for+OLIF51+by+non-enhanced+MRI+and+CT+medical+image+fusion+technique.">Assessment of 3D lumbosacral vascular anatomy for OLIF51 by non-enhanced MRI and CT medical image fusion technique.</a> Diagnostics. 11 (10), 1744 (2021).</li><li>Tanaka, M., Fujiwara, Y., Uotani, K., Maste, P., Yamauchi, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=C-arm-free+circumferential+minimally+invasive+surgery+for+adult+spinal+deformity:+Technical+note.">C-arm-free circumferential minimally invasive surgery for adult spinal deformity: Technical note.</a> World Neurosurgery. 143, 235-246 (2020).</li></ol>

最近，用于椎间融合的侧腰椎方法因其微创性而越来越受欢迎9。在这些方法中，直接侧向腰大肌分裂方法有几个缺点，如腰神经丛损伤和腰大肌无力10。为了减少这些并发症，戴维斯等人在2014年引入了预置骨灰质或OLIF11。然而，由于其解剖学特征，很难在L5-S1椎间盘上操作。2017年，设计了一种新技术，以横向位置（OLIF51）接近L5-S1椎间盘，使?...

脊柱病被认为是应力性骨折1 ，发生在约5%的年轻成年人群中2。最常见的发生水平是在L5水平，因为在L5-S1区域施加了独特的剪切力。脊柱病和脊柱滑脱的主要症状是腰痛、腿部疼痛和麻木。如果保守治疗无效，建议手术治疗3.经椎间孔腰椎间融合术 （TLIF） 是一种有效且成熟的技术4，但该手术的非骨折发生率在 L5-S1级别 5 时相对较高。此外，与斜腰椎椎体间融合术 （OLIF） 或前腰椎体间融合术 （ALIF） 相比，TLIF 很难产生足够的脊柱前凸6。
间接减压（如ALIF或OLIF）是目前治疗腰椎管狭窄的常用方法7。然而，传统的ALIF技术会导致大量的肌肉损伤。L5-S1水平（OLIF51）的斜侧向体间融合于2017年首次报道8。通常需要后部器械增强以确保固体融合，但传统的OLIF技术使用C型臂，并且患者位置从侧向改为俯卧。为了克服这些问题，我们在这里报告了一种在单个横向位置上无C臂同时OLIF51和经皮椎弓根螺钉（PPS）的新技术。 
我们介绍一名75岁妇女患有有症状的L5脊柱滑脱（2级）的病例。

<table border="1" fo:keep-together.within-page="1" fo:keep-with-next.within-page="always">
	<tbody>
		<tr>
			<td>Adjustable hinged operating carbon table</td>
			<td>Mizuho OSI</td>
			<td>6988A-PV-ACP</td>
			<td>OSI Axis Jackson table</td>
		</tr>
		<tr>
			<td>CD Horizon Solera Voyager</td>
			<td>Medtronic</td>
			<td>6.4317E+11</td>
			<td>Percutaneous pedicle screw system</td>
		</tr>
		<tr>
			<td>Navigated Cobb elevator</td>
			<td>Medtronic</td>
			<td>NAV2066</td>
			<td></td>
		</tr>
		<tr>
			<td>Navigated combo tool</td>
			<td>Medtronic</td>
			<td>NAV2068</td>
			<td></td>
		</tr>
		<tr>
			<td>Navigated curette</td>
			<td>Medtronic</td>
			<td>NAV2069</td>
			<td></td>
		</tr>
		<tr>
			<td>Navigated high speed bur</td>
			<td>Medtronic</td>
			<td>EM200N</td>
			<td>Stelth</td>
		</tr>
		<tr>
			<td>Navigated passive pointer</td>
			<td>Medtronic</td>
			<td>960-559</td>
			<td></td>
		</tr>
		<tr>
			<td>Navigated pedicle probe</td>
			<td>Medtronic</td>
			<td>9734680</td>
			<td></td>
		</tr>
		<tr>
			<td>Navigated shaver</td>
			<td>Medtronic</td>
			<td>NAV2071</td>
			<td></td>
		</tr>
		<tr>
			<td>NIM Eclipse system</td>
			<td>Medtronic</td>
			<td>ECLC</td>
			<td>Neuromonitouring</td>
		</tr>
		<tr>
			<td>O-arm</td>
			<td>Medtronic</td>
			<td>224ABBZX00042000</td>
			<td>Intraoperative CT</td>
		</tr>
		<tr>
			<td>Radiolucent open spine cramp</td>
			<td>Medtronic</td>
			<td>9731780</td>
			<td></td>
		</tr>
		<tr>
			<td>Self-retaining retractor</td>
			<td>Medtronic</td>
			<td>29B2X10008MDT151</td>
			<td></td>
		</tr>
		<tr>
			<td>Sovereign Spinal System</td>
			<td>Medtronic</td>
			<td>6.4317E+11</td>
			<td>OLIF51 cage</td>
		</tr>
		<tr>
			<td>Spine small passive frame</td>
			<td>Medtronic</td>
			<td>9730605</td>
			<td></td>
		</tr>
		<tr>
			<td>Stealth station navigation system Spine 7R</td>
			<td>Medtronic</td>
			<td>9733990</td>
			<td>Navigation</td>
		</tr>
		<tr>
			<td>U-NavLock Gray</td>
			<td>Medtronic</td>
			<td>9734590</td>
			<td></td>
		</tr>
		<tr>
			<td>U-NavLock Green</td>
			<td>Medtronic</td>
			<td>9734734</td>
			<td></td>
		</tr>
		<tr>
			<td>U-NavLock Orange</td>
			<td>Medtronic</td>
			<td>9734683</td>
			<td></td>
		</tr>
		<tr>
			<td>U-NavLock Violet</td>
			<td>Medtronic</td>
			<td>9734682</td>
			<td></td>
		</tr>
	</tbody>
</table>

c-arm-free simultaneous olif51 and percutaneous pedicle screw fixation in a single lateral position

斜腰椎体间融合术 （OLIF） 是一种用于间接减压腰椎管狭窄的成熟技术。然而，由于解剖学结构的原因，L5-S1级别的OLIF（OLIF51）在技术上是困难的。我们提出了一种新颖的OLIF51同步技术，经皮椎弓根螺钉固定，无需透视。将患者置于右侧卧位。将经皮参考销插入右骶髂关节。执行O型臂扫描，并将3D重建图像传输到脊柱导航系统。在沿着骨盆的导航引导下做一个4厘米的斜皮肤切口。腹内/外和横腹肌沿着肌纤维分开，保护髂下腹神经和髂腹股沟神经。使用腹膜后入路，可识别左髂总血管。带有照明的特殊肌肉牵开器用于暴露L5-S1椎间盘。使用导航仪器准备光盘后，光盘空间会因导航试验而分散注意力。然后将自生骨和脱矿质骨材料插入笼孔中。OLIF51笼子在木槌的帮助下插入光盘空间。同时，经皮椎弓根螺钉由另一位外科医生插入，而不改变患者的侧卧位。
总之，在导航引导下，在横向位置进行无C臂OLIF51和同时经皮椎弓根螺钉固定。这种新技术减少了手术时间和辐射危害。

14例（平均年龄：71.5岁）使用这种新技术进行治疗。他们将他们与L5-S1 TLIF的40例（平均年龄：74.0岁）进行比较。两组均测定L5-S1前凸角和椎间盘高度。OLIF51组获得比TLIF 51组更好的L5-S1前凸（图15）。
<img alt="Figure 15" class="xfigimg" src="/files/ftp_upload/63572/63572fig15.jpg"> 图 15：放射?...

Watch this Scientific Journal Video about C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position at JoVE.com

C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position

在导航引导下，在横向位置进行 L5-S1 水平 （OLIF51） 的无 C 臂倾斜腰椎间融合术和同时的椎弓根螺钉固定。这种技术不会使外科医生或手术人员暴露于辐射危害。

无 C 型臂同时 OLIF51 和经皮椎弓根螺钉固定在单个侧位

Oblique lumbar interbody fusion (OLIF) is an established technique for the indirect decompression of lumbar canal stenosis. However, OLIF at the L5-S1 ...

脊柱病被认为是应力性骨折，发生在约5%的年轻人群中。最常见的发生水平是L5水平，因为在L5-S1区域施加了独特的剪切力。脊柱病和脊柱滑脱的主要症状是腰痛、腿部疼痛和麻木。如果保守治疗证明无效，建议进行手术治疗。经椎间孔腰椎间融合术，TLIF是一种有效且成熟的技术，但该手术的非愈合率在L5-S1水平相对较高。此外，与斜腰椎体间融合术（ORIF）或前腰椎体间融合术（ALIF）相比，TLIF很难减少前凸。内部减压（如 ALIF 或 ORIF）是目前治疗腰椎管狭窄的常用方法。然而，压缩方法会导致大量的肌肉损伤。OLIF处于5-S1水平，OLIF-51于2017年首次报告。后韧带增大术通常是必要的，以确保实体融合，但传统的OLIF技术使用C型臂，患者位置从侧向改为俯卧。为了克服这些问题，我们提出了一种新颖的技术，即无C型臂同时将椎弓根螺钉固定在单个横向位置。在本视频中，我们介绍了一例75岁女性的症状性L5脊柱滑脱。这项研究得到了冈山罗赛医院埃塞克斯委员会的批准。这是无C型臂同时进行OLIF-51和经皮椎弓根螺钉固定的方案。检查术前图像。功能性放射图有助于我们评估脊柱不稳定性。核磁共振成像为我们提供了神经盘的信息。CT 扫描对于检查骨骼结构非常重要。由L5-S1椎间盘水平的常见髂血管组成的血管窗口通过CT MRI融合图像清楚地显示出来。该过程在全身麻醉下进行。手术台应为全碳工作台，用O型臂进行CT扫描。这是Pro轴，可调节的全碳工作台。用胶带以浅侧卧位压患者。如果可能，建议进行神经监测，以防止OLIF期间的神经系统并发症。我们使用南洋神经监测系统。将导航参考系经皮压入骶髂关节。然后设置O型臂并进行术中CT扫描。沿着peri做4厘米的上部皮肤切口，然后与皮肤切口一起分割并解剖腹部肌肉。暴露后，用蓝色自保留牵开器识别左髂总血管并逐渐离开，消除。导航的探测器用于检查 L5-S1 磁盘空间。绿色等级是缩回右侧的普通髂血管。浅蓝色等级是缩回髂总血管的分叉。现在，您可以非常清楚地看到L5-S1光盘。用刀切开环，使用垂体镊子进行椎间盘切除术。使用导航指针，您可以在没有C型臂的情况下以3D方式确认解剖结构。这是连字。这是一个导航组合工具，使企业顺利进行。这是导航剃须刀。这是导航试用版。对于 OLIF-51，保持架尺寸为 10 至 16 毫米，机器人保持架角度为 8、12、18 度。用木槌插入笼子。插入保持架后，插入一个辅助螺钉。另一位外科医生同时进行经皮椎弓根螺钉固定术。这些是术后放射造影。这种新技术有14个案例。与40例TLIF-51术前L5-S1相比，OLIF-51和TLIF-51的L5-S1角度分别为11.4度和10.1度。这些差异并不显著。然而，OLIF-51和TLIF-51的术后L5-S1角分别为21.3度和12个1点度。这些结果在统计学上是不同的。OLIF-51组术后L5-S1椎间盘高度均高于TLIF-51组。我们方法的关键步骤。首先，术前准备髂总血管的位置非常重要，因为血管窗口，小于20毫米的导联呈现OLIF-51的禁忌症。第二。差框销应经皮牢固地插入左SI关节。如果移动差异框架，则该过程的准确性，不会冒着螺钉或笼子错位的风险，第三，导航仪器，包括指针，椎弓根探头，剃须刀应有效使用作为C型臂技术的替代方法也适用于这种同时方法，并且必须考虑该技术的某些局限性。相对昂贵的设备，如O型臂和导航系统是必要的。这种技术的学习曲线陡峭。有必要以病例系列的形式进行进一步的研究，以确保该技术对治疗缺血性脊柱滑脱仍然有效。总之，在导航引导下，在单个侧向位置同时进行C型臂游离OLIF-51和经皮椎弓根螺钉固定。这种新技术减少了手术时间和外科医生和手术人员的辐射危害。感谢您的关注。

Research

JoVE Journal

Medicine

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS

延髓功能障碍肌萎缩性脊髓侧索硬化症（ALS）的综合评估议定书

Improved methods for assessing bulbar impairment are necessary for expediting diagnosis of bulbar dysfunction in ALS, for predicting disease progression ...

科研

医学

A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice

一个简单的指南螺杆颅内移植瘤小鼠的研究方法

The grafting of human tumor cells into the brain of immunosuppressed mice is an established method for the study of brain cancers including glioblastoma ...

Preparation and Respirometric Assessment of Mitochondria Isolated from Skeletal Muscle Tissue Obtained by Percutaneous Needle Biopsy

线粒体的制备及透气性评估，从骨骼肌组织通过穿刺活检获得的分离

Respirometric profiling of isolated mitochondria is commonly used to investigate electron transport chain function. We describe a method for obtaining ...

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

在体内 ，经皮，基于针，肾群众的光学相干断层扫描

Optical coherence tomography (OCT) is the optical equivalent of ultrasound imaging, based on the backscattering of near infrared light. OCT provides real ...

Instillation and Fixation Methods Useful in Mouse Lung Cancer Research

灌输和固定方法有用的小鼠肺癌研究

The ability to instill live agents, cells, or chemicals directly into the lung without injuring or killing the mice is an important tool in lung cancer ...

Imaging- and Flow Cytometry-based Analysis of Cell Position and the Cell Cycle in 3D Melanoma Spheroids

单元位置的Imaging-和流式细胞仪为基础的分析和3D球体黑色素瘤细胞周期

Three-dimensional (3D) tumor spheroids are utilized in cancer research as a more accurate model of the in vivo tumor microenvironment, compared to ...

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model

经皮超声心动图引导心肌注射液与大鼠前体细胞的临床研究

Cell and gene therapy are exciting and promising strategies for the purpose of cardiac regeneration in the setting of heart failure with reduced ejection ...

Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

成年大鼠脊髓侧性横断与不对称行为评估

Incomplete spinal cord injury (SCI) often leads to impairments of sensorimotor functions and is clinically the most frequent type of SCI. Human ...

Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis

慢性胰腺炎的机器人侧胰腺肌切除术

Lateral pancreaticojejunostomy (LPJ) has shown good postoperative outcomes in patients with painful, morphine dependent, chronic pancreatitis (CP). The ...

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model

猪模型中经皮栓塞线圈部署的心肌梗死

Myocardial infarction (MI) is the leading cause of mortality worldwide. Despite the use of evidence-based treatments, including coronary revascularization ...