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09:09 min
August 17th, 2022
DOI :
10.3791/64095-v
Chapters
0:04
Introduction
0:48
Baseline Immunoreactivity (BIR) Testing
1:56
Tail Bleed Method for Blood Collection
3:23
Weight Based Method for Mating and Gestational Embryonic Day 12.5 Injection
5:34
Investigation of Alterations in Behavior in Adult MIA and Control Offspring (Optional)
6:35
Results: Investigating Susceptibility and Resilience of Offspring to Maternal Immune Activation
8:15
Conclusion
Transcript
Maternal infection, including SARS
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Summary
母体感染是神经发育障碍的危险因素。母体免疫激活(MIA)小鼠模型可以阐明感染对大脑发育和功能的影响。在这里,提供了一般指南和程序,以产生暴露于MIA的可靠弹性和易感后代。
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