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Please note that all translations are automatically generated. Click here for the English version.
1.2K Views
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01:38 min
November 3rd, 2023
DOI :
10.3791/65259-v
Transcript
我们的实验室正在努力了解、预防和逆转 1 型和 2 型糖尿病的 β 细胞功能障碍和其他眼睑异常。我们的研究重点是通过整合人类胰腺和眼睑生物学以及健康和疾病的研究来研究人类糖尿病的发病机制。人类孔眼是3D球形结构,在整个孔眼中访问细胞会带来一些实验挑战。
例如,当尝试引入生物传感器来理解孔眼细胞信号传导时,我们的假眼睑方案通过在单细胞状态下进行遗传操作并将这些转导的人眼细胞聚集到假眼睑中以进行下游研究来克服这一挑战。我们的假眼睑系统使我们能够在整个孔眼中表达生物传感器,而不仅仅是
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