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Please note that all translations are automatically generated. Click here for the English version.
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02:32 min
January 26th, 2024
DOI :
10.3791/65646-v
Transcript
该协议为抗原特异性CD8 T细胞的研究提供了有用的生殖模型。它们是淋巴结转移,排除了旁观者 CD8 T 细胞的参与。我们试图揭示抗原特异性CD8 T细胞的全身和局部动力学,它们是淋巴结转移。
最近积累的证据表明,来源于外周的肿瘤特异性CD8 T细胞,特别是在肿瘤引流淋巴结中,但在肿瘤微环境中却没有达到免疫检查点阻断治疗的疗效。最近,我们在小鼠肿瘤模型和人肝细胞癌患者的肿瘤引流淋巴结中的一个阳性、阴性肿瘤亚特异性记忆 T 细胞中发现了这一点,这些 T 细胞作为免疫检查点阻断的一般
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