Research
Education
Sign In
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
TR - Turkish
JA - Japanese
Please note that all translations are automatically generated. Click here for the English version.
204 Views
•
02:07 min
May 3rd, 2024
DOI :
10.3791/66784-v
Transcript
我们的研究小组正试图了解人体肌间脂肪组织或IMAT的细胞组成和细胞特异性转录谱。IMAT实际上是一种异位脂肪库,位于肌肉纤维之间和周围。计算机断层扫描和 MRI 已经能够量化 IMAT 体积,最近表明它随着年龄和 BMI 的增加而增加,并且还与肌肉退行性疾病有关。
体外分泌组研究最近表明,IMAT分泌蛋白具有影响胰岛素敏感性、炎症特征以及人骨骼肌中收缩蛋白表达的能力。活检过程中收集的IMAT组织数量有限,脂肪细胞富含脂质,使得该组织与组织消化和单细胞RNA-Seq不相容。因此,
Sign in or start your free trial to access this content
Explore More Videos
From the series
Privacy
Terms of Use
Policies
Contact Us
Recommend to library
JoVE NEWSLETTERS
JoVE Journal
Methods Collections
JoVE Encyclopedia of Experiments
Archive
JoVE Core
JoVE Business
JoVE Science Education
JoVE Lab Manual
Faculty Resource Center
Authors
Librarians
Access
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved