September 12th, 2016
•This protocol describes how to determine whether pharmacological treatments for experimental autoimmune encephalomyelitis show CNS protection as a consequence of suppressing immune cell infiltration or are neuroprotective during the onslaught of immune cell infiltration.
Tags
Related Videos
Seven Steps to Stellate Cells
Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis (EAE) Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge
Detection of MicroRNAs in Microglia by Real-time PCR in Normal CNS and During Neuroinflammation
Culturing Microglia from the Neonatal and Adult Central Nervous System
Isolation of Infiltrating Leukocytes from Mouse Skin Using Enzymatic Digest and Gradient Separation
Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
Isolating Lymphocytes from the Mouse Small Intestinal Immune System
Adoptive Immunotherapy of iNKT Cells in Glucose-6-Phosphate Isomerase (G6PI)-Induced RA Mice
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved